黄曲霉毒素B2：化学特性与生物活性。
AFLATOXIN B2: CHEMICAL IDENTITY AND BIOLOGICAL ACTIVITY.
作者信息
CHANG S B, ABDEL-KADER M M, WICK E L, WOGAN G N
出版信息
Science. 1963 Nov 29;142(3596):1191-2. doi: 10.1126/science.142.3596.1191.
Abstract
Aflatoxin B(2), a blue-fluorescent metabolite of Aspergillus flavus, was isolated from cultures grown on crushed wheat. Chemical structure of the compound was elucidated as dihydroaflatoxin B(1). Biological activity was determined in day-old male white Pekin ducklings. The criteria of activity were reduction in growth and liver size and the extent of bile-duct hyperplasia.
摘要
黄曲霉毒素B(2)是黄曲霉菌产生的一种蓝色荧光代谢产物，从碾碎小麦上培养出的菌中分离得到。该化合物的化学结构被阐明为二氢黄曲霉毒素B(1)。在1日龄雄性北京鸭雏鸭中测定了其生物活性。活性标准为生长和肝脏大小的降低以及胆管增生的程度。
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