脑积液与多发性硬化症的发病机制
Fluids of the brain and the pathogenesis of MS.
作者信息
Thompson E J, Zeman A
机构信息
Department of Neurochemistry, Institute of Neurology, London.
出版信息
Neurochem Res. 1992 Sep;17(9):901-5. doi: 10.1007/BF00993266.
PMID:1407277
Abstract
The plaques of multiple sclerosis are generally thought to spread outwards from central veins. We propose that periventricular plaques in the cerebral hemispheres, and superficial plaques in the brain stem and spinal cord, point to the importance of demyelinating factors in the cerebrospinal fluid.
摘要
多发性硬化症的斑块通常被认为是从中央静脉向外扩散的。我们提出，大脑半球的脑室周围斑块以及脑干和脊髓的浅表斑块表明脑脊液中脱髓鞘因子的重要性。
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