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脑脊液生成：霍乱毒素的刺激作用

Cerebrospinal fluid production: stimulation by cholera toxin.

作者信息

Epstein M H, Feldman A M, Brusilow S W

出版信息

Science. 1977 May 27;196(4293):1012-3. doi: 10.1126/science.193189.

DOI:10.1126/science.193189
PMID:193189
Abstract

Large increases in the production of cerebrospinal fluid have been observed after the intraventricular administration of cholera toxin. Because cholera toxin stimulates adenylate cyclase, the data suggest that adenosine 3',5'-monophosphate plays a role in cerebrospinal fluid production.

摘要

在脑室内注射霍乱毒素后，观察到脑脊液生成大幅增加。由于霍乱毒素刺激腺苷酸环化酶，这些数据表明3',5'-环磷酸腺苷在脑脊液生成中起作用。

相似文献

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Cerebrospinal fluid production: stimulation by cholera toxin.脑脊液生成：霍乱毒素的刺激作用
Science. 1977 May 27;196(4293):1012-3. doi: 10.1126/science.193189.
2
Activation by cholera toxin of adenylate cyclase solubilized from rat liver.霍乱毒素对从大鼠肝脏中溶解出的腺苷酸环化酶的激活作用。
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Altered guanine nucleotide hydrolysis as basis for increased adenylate cyclase activity after cholera toxin treatment.霍乱毒素处理后鸟嘌呤核苷酸水解改变作为腺苷酸环化酶活性增加的基础。
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Rat pancreas adenylate cyclase. III. Its role in pancreatic secretion assessed by means of choleara toxin.大鼠胰腺腺苷酸环化酶。III. 通过霍乱毒素评估其在胰腺分泌中的作用。
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Mode of action of cholera toxin: stabilization of catecholamine-sensitive adenylate cyclase in turkey erythrocytes.霍乱毒素的作用模式：火鸡红细胞中儿茶酚胺敏感型腺苷酸环化酶的稳定作用
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Infect Immun. 1975 Feb;11(2):343-9. doi: 10.1128/iai.11.2.343-349.1975.

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