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IN VITRO STUDY OF HUMAN RECTAL EPITHELIAL CELLS. I. ATYPICAL ZONE OF H3 THYMIDINE INCORPORATION IN MUCOSA OF MULTIPLE POLYPOSIS.

作者信息

DESCHNER E, LEWIS C M, LIPKIN M

出版信息

J Clin Invest. 1963 Dec;42(12):1922-8. doi: 10.1172/JCI104878.

DOI:10.1172/JCI104878
PMID:14086779
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC289480/
Abstract
摘要
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/2514/289480/664ace1bd778/jcinvest00288-0102-b.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/2514/289480/081e894d11f9/jcinvest00288-0099-a.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/2514/289480/98888d0dc7af/jcinvest00288-0099-b.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/2514/289480/f79c12cc4ad3/jcinvest00288-0101-a.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/2514/289480/d418810b5360/jcinvest00288-0102-a.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/2514/289480/664ace1bd778/jcinvest00288-0102-b.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/2514/289480/081e894d11f9/jcinvest00288-0099-a.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/2514/289480/98888d0dc7af/jcinvest00288-0099-b.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/2514/289480/f79c12cc4ad3/jcinvest00288-0101-a.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/2514/289480/d418810b5360/jcinvest00288-0102-a.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/2514/289480/664ace1bd778/jcinvest00288-0102-b.jpg

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本文引用的文献

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CELL PROLIFERATION KINETICS IN THE GASTROINTESTINAL TRACT OF MAN. I. CELL RENEWAL IN COLON AND RECTUM.人类胃肠道中的细胞增殖动力学。I. 结肠和直肠中的细胞更新
J Clin Invest. 1963 Jun;42(6):767-76. doi: 10.1172/JCI104769.
2
Induction of tumours in mice with tritiated thymidine.用氚标记的胸腺嘧啶核苷诱导小鼠肿瘤
Nature. 1961 Nov 11;192:571-2. doi: 10.1038/192571a0.
3
Generation time of epithelial cells in the human colon.
Nature. 1962 Jul 14;195:175-7. doi: 10.1038/195175b0.
一种APC:WNT逆流样机制沿人类结肠隐窝轴调节细胞分裂：一种解释APC突变如何诱导增殖异常从而驱动结肠癌发展的机制。
Front Oncol. 2013 Nov 7;3:244. doi: 10.3389/fonc.2013.00244.
4
Identification of a developmental gene expression signature, including HOX genes, for the normal human colonic crypt stem cell niche: overexpression of the signature parallels stem cell overpopulation during colon tumorigenesis.鉴定出一种发育相关的基因表达特征，包括 HOX 基因，用于正常人类结肠隐窝干细胞生态位：该特征的过表达与结肠癌发生过程中的干细胞过度增殖相平行。
Stem Cells Dev. 2014 Jan 15;23(2):167-79. doi: 10.1089/scd.2013.0039. Epub 2013 Nov 5.
5
Survivin-induced Aurora-B kinase activation: A mechanism by which APC mutations contribute to increased mitoses during colon cancer development.Survivin 诱导的 Aurora-B 激酶激活：APC 突变促进结肠癌发展过程中细胞有丝分裂增加的一种机制。
Am J Pathol. 2010 Dec;177(6):2816-26. doi: 10.2353/ajpath.2010.100047. Epub 2010 Nov 5.
6
Molecular models for the tissue specificity of DNA mismatch repair-deficient carcinogenesis.DNA错配修复缺陷致癌作用组织特异性的分子模型。
Nucleic Acids Res. 2006 Feb 6;34(3):840-52. doi: 10.1093/nar/gkj489. Print 2006.
7
Colonic crypt changes during adenoma development in familial adenomatous polyposis: immunohistochemical evidence for expansion of the crypt base cell population.家族性腺瘤性息肉病腺瘤发生过程中的结肠隐窝变化：隐窝基底细胞群扩张的免疫组化证据
Am J Pathol. 2004 Nov;165(5):1489-98. doi: 10.1016/S0002-9440(10)63407-4.
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Aberrant crypt foci in colorectal carcinogenesis. Cell and crypt dynamics.结直肠癌发生过程中的异常隐窝病灶。细胞和隐窝动态变化。
Cell Prolif. 2000 Feb;33(1):1-18. doi: 10.1046/j.1365-2184.2000.00159.x.
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Proliferation and differentiation biomarkers in colorectal mucosa and their application to chemoprevention studies.结直肠黏膜中的增殖和分化生物标志物及其在化学预防研究中的应用。
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Proliferating cell nuclear antigen/cyclin expression in small adenomas of the large intestine in relation to size and macroscopic appearance.大肠小腺瘤中增殖细胞核抗原/细胞周期蛋白表达与大小及大体外观的关系
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4
Genetic factors in intestinal polyposis.肠息肉病中的遗传因素。
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5
Mutations induced in the mouse with tritiated thymidine.用氚标记的胸腺嘧啶核苷在小鼠中诱导的突变。
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Uptake of tritiated thymidine by human tumors in vivo.体内人肿瘤对氚标记胸腺嘧啶核苷的摄取。
Lab Invest. 1962 May;11:360-4.
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Clinical and genetic problems in familial in-intestinal polyposis.家族性肠息肉病的临床与遗传学问题
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Am J Anat. 1960 May;106:247-85. doi: 10.1002/aja.1001060305.
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Observations of cell renewal in human rectal mucosa in vivo with thymidine-H3.用氚标记胸腺嘧啶核苷对人体直肠黏膜细胞更新进行的体内观察。
Gastroenterology. 1961 Aug;41:122-5.
10
Cell population kinetics in the intestinal epithelium of the mouse.小鼠肠道上皮中的细胞群体动力学
Exp Cell Res. 1959 Jun;17(3):420-38. doi: 10.1016/0014-4827(59)90063-1.