淋巴细胞相互作用：一种潜在的体外组织相容性试验。

LYMPHOCYTE INTERACTION: A POTENTIAL HISTOCOMPATIBILITY TEST IN VITRO.

作者信息

BACH F, HIRSCHHORN K

出版信息

Science. 1964 Feb 21;143(3608):813-4. doi: 10.1126/science.143.3608.813.

DOI:10.1126/science.143.3608.813

Abstract

Lymphocytes from two unrelated individuals, cultured together in the same tube, undergo morphological transformation to large cells and divide. Both of these parameters may be estimated quantitatively. There is a correlation between the degree of this response and the degree of cross-reactivity of grafts from the two individuals placed on a third unrelated recipient.

摘要

来自两个不相关个体的淋巴细胞，在同一试管中共同培养时，会发生形态转变成为大细胞并进行分裂。这两个参数都可以进行定量评估。这种反应的程度与将这两个个体的移植物移植到第三个不相关受体上的交叉反应程度之间存在相关性。