Matturri L, Azzolini A, Riberti C, Lavezzi A M, Cavalca D, Vercesi F, Azzolini C
Institute of Pathology, University of Milan, Italy.
Plast Reconstr Surg. 1992 Oct;90(4):636-42. doi: 10.1097/00006534-199210000-00013.
Forty-two patients operated on by skin expansion have been contacted after a mean time of 25 months from the last surgery. Two biopsies have been taken from the expanded area of each patient. In 12 patients it has been possible to obtain a similar sampling from the opposite, nonexpanded area of the body. The samples underwent optic microscopy and cell kinetic and DNA content investigations. The epidermal structure of the followed-up skin, compared with the skin of the opposite side of the body, looks normal. The mitotic activity of the epidermal cells has returned to the values of preexpanded skin. The dermis shows a low degree of elastosis and zonal fragmentation of elastic fibers. The hypodermis, where the expander capsule was removed during the last surgery, does not show an accentuated fibrosis.
自最后一次手术起平均25个月后，已联系到42名接受皮肤扩张手术的患者。从每位患者的扩张区域取了两块活检组织。在12名患者中，还从身体相对的未扩张区域获取了类似样本。样本进行了光学显微镜检查、细胞动力学和DNA含量研究。随访皮肤的表皮结构与身体另一侧的皮肤相比，看起来正常。表皮细胞的有丝分裂活性已恢复到扩张前皮肤的值。真皮显示出低度弹性组织变性和弹性纤维的带状断裂。皮下组织在最后一次手术中已移除扩张器包膜，未显示出明显的纤维化。
