[Chromosome aberration induction in murine spermatocytes in joint exposure to radiation and sodium nitrite and nitrate].

In studying the combined effect of single and fractionated exposure to gamma/neutron radiation (12.5-50 cGy) and sodium nitrite (100 mg/kg) and chronic irradiation with a mixture of radiation (25 cGy) and sodium nitrite, nitrate (10-100 mg/l) the synergistic effect was observed in inducing reciprocal translocations in mouse spermatocytes. The dose-response function of the reciprocal translocations occurrence in Af mouse spermatocytes was nonlinear; there was a "plateau" within the dose range from 25 to 50 cGy.