[慢性低剂量γ射线照射小鼠生殖细胞中的染色体易位]

[Chromosome translocations in the sex cells of mice subjected to chronic low-dose gamma-irradiation].

作者信息

Baĭrakova A K, Rupova I M, Vasilev G G

出版信息

Genetika. 1977;13(9):1561-4.

Abstract

Translocation induction in mouse spermatogonia by continuous whole-body gamma irradiation (radium 226) was studied. Total doses, delivered at a rate of 13.0 +/- 1.3 X 10(-4) rad/min for various time intervals, were 97, 195, 294 and 442 rad. Cytological examination within 3 to 4 months after irradiation indicated the presence of translocations in 0.16, 0.30, 0.75 and 1.29 percent respectively, of primary spermatocytes at diakinesis metaphase I. Data on translocation induction (Y) as related to total irradiation dose (D) were best fitted to a second power parabola equation (Y=5.1 X 10(-6)D2 + 7.32 X 10(-4) X D). The results obtained confirm that chronic gamma irradiation is of low genetic efficiency, and support the suggestion that there exists a dose-rate threshold under which no more changes in exposure efficiency will occur.

摘要

研究了通过连续全身γ射线照射（镭226）诱导小鼠精原细胞易位的情况。以13.0±1.3×10⁻⁴拉德/分钟的速率在不同时间间隔给予的总剂量分别为97、195、294和442拉德。照射后3至4个月内的细胞学检查表明，在第一次减数分裂中期终变期的初级精母细胞中，易位的出现率分别为0.16%、0.30%、0.75%和1.29%。与总照射剂量（D）相关的易位诱导数据（Y）最符合二次幂抛物线方程（Y = 5.1×10⁻⁶D² + 7.32×10⁻⁴×D）。获得的结果证实，慢性γ射线照射的遗传效率较低，并支持存在剂量率阈值的观点，低于该阈值，照射效率不会再发生变化。

相似文献

1

[Chromosome translocations in the sex cells of mice subjected to chronic low-dose gamma-irradiation].[慢性低剂量γ射线照射小鼠生殖细胞中的染色体易位]

Genetika. 1977;13(9):1561-4.

2

[Mutagenic effect of different types of radiation on the sex cells of male mice. VIII. Frequency of development of reciprocal translocations in the spermatogonia of mice subjected to chronic gamma radiation].[不同类型辐射对雄性小鼠生殖细胞的诱变作用。VIII. 受慢性γ辐射的小鼠精原细胞中相互易位的发生频率]

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[The mutagenic effect of different types of irradiation on the sex cells of male mice. VIII. Frequency of development of reciprocal translocations in the spermatogonia of mice subjected to chronic gamma-irradiation].[不同类型辐射对雄性小鼠生殖细胞的诱变作用。VIII. 慢性γ辐射小鼠精原细胞中相互易位的发生频率]

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Genetika. 1975;11(3):81-6.

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[Mutagenic effect of different types of irradiation on the sex cells of male mice. IX. Duration of preservation of radiation-induced reciprocal translocations during the course of the reproductive period].[不同类型辐射对雄性小鼠生殖细胞的诱变作用。IX. 生殖期内辐射诱导的相互易位的保存时间]

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[Genetic effect of chronic gamma radiation exposure in male mice].[慢性γ辐射暴露对雄性小鼠的遗传效应]

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[Cytogenetic effect of 238Pu alpha radiation on the germ cells of male mice].[238Puα辐射对雄性小鼠生殖细胞的细胞遗传学效应]

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[Dominant lethality and translocations in the sex cells of male rats under low-intensity gamma irradiation].[低强度γ射线照射下雄性大鼠生殖细胞中的显性致死和易位]

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RBE values of d (16) + Be and d (50) + Be neutrons for chromosome rearrangements induced in mouse spermatogonia.用于诱导小鼠精原细胞中染色体重排的氘（16）+铍和氘（50）+铍中子的相对生物效应值。

Strahlentherapie. 1977 Jun;153(6):423-5.

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