[Prostacyclin-thromboxane system in children and adolescents with a high risk of developing ischemic heart disease].

Studies of the prostacyclin-thromboxane system in children and juveniles of 7-18 years old with hereditary ischemic heart disease demonstrated that the hereditary factor proved to be of importance for the system state. Alterations of prostanoids in these children and juveniles were related to atherogenesis development, particularly to hyperproduction of thromboxane A2, whereas patterns of the system studied varied depending on sex and family history.