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实验性糖尿病中的周围神经纤维大小

Peripheral nerve fiber size in experimental diabetes.

作者信息

Sharma A K, Thomas P K, De Molina A F

出版信息

Diabetes. 1977 Jul;26(7):689-92. doi: 10.2337/diab.26.7.689.

DOI:10.2337/diab.26.7.689
PMID:141385
Abstract

Serial morphometric observations were made on the tibial nerves of mature rats before and five weeks after the induction of diabetes by streptozotocin. Maximum and average myelinated fiber diameter did alter, neither did the relationship between myelin sheath thickness and axon circumference. This confirms previous observations suggesting that the reduced nerve conduction velocity that is known to occur in experimental diabetes is likely to depend on metabolic alterations rather than on structural changes.

摘要

对成年大鼠的胫神经进行了系列形态测量观察,观察时间为链脲佐菌素诱导糖尿病之前及之后五周。有髓纤维的最大直径和平均直径确实发生了变化,髓鞘厚度与轴突周长之间的关系也没有变化。这证实了先前的观察结果,即实验性糖尿病中已知发生的神经传导速度降低可能取决于代谢改变而非结构变化。

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Peripheral nerve fiber size in experimental diabetes.实验性糖尿病中的周围神经纤维大小
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引用本文的文献

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Association of chronic diabetes and hypertension in sural nerve morphometry: an experimental study.慢性糖尿病和高血压与腓肠神经形态计量学的关系:一项实验研究。
Diabetol Metab Syndr. 2015 Feb 15;7:9. doi: 10.1186/s13098-015-0005-8. eCollection 2015.
2
Renal nerve ultrastructural alterations in short term and long term experimental diabetes.短期和长期实验性糖尿病肾神经超微结构改变。
BMC Neurosci. 2014 Jan 5;15:5. doi: 10.1186/1471-2202-15-5.
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Effects of Nigella sativa and its major constituent, thymoquinone on sciatic nerves in experimental diabetic neuropathy.
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Neurochem Res. 2008 Jan;33(1):87-96. doi: 10.1007/s11064-007-9419-5. Epub 2007 Aug 23.
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Giant axonopathy in streptozotocin diabetes of rats.大鼠链脲佐菌素糖尿病中的巨大轴索性神经病
Acta Neuropathol. 1993;86(1):42-8. doi: 10.1007/BF00454897.
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Sciatic nerve morphology and morphometry in mature rats with streptozocin-induced diabetes.
Acta Neuropathol. 1994;88(6):571-8. doi: 10.1007/BF00296495.
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Age changes in the tibial and plantar nerves of the rat.大鼠胫神经和足底神经的年龄变化
J Anat. 1980 Mar;130(Pt 2):417-28.
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Nerve conduction velocity in experimental diabetes in the rat and rabbit.大鼠和家兔实验性糖尿病中的神经传导速度
J Neurol Neurosurg Psychiatry. 1981 Mar;44(3):233-8. doi: 10.1136/jnnp.44.3.233.
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