Davis C D, Malecki E A, Greger J L
Department of Nutritional Sciences, University of Wisconsin-Madison 53706-1571.
Am J Clin Nutr. 1992 Nov;56(5):926-32. doi: 10.1093/ajcn/56.5.926.
The relationship among dietary intake of heme iron, nonheme iron, and manganese on indexes of hematological and nutritional status in regard to manganese of 47 women consuming their typical diets was investigated. Increasing dietary iron intake, by consuming more nonheme iron in the diet, had questionable effects on hematological status (hematocrit values and ferritin and transferrin concentrations) and negative effects on nutritional status in regard to manganese (serum manganese, urine manganese, and lymphocyte manganese-dependent superoxide dismutase activity). In contrast, heme-iron intake was positively correlated with hematological status and had no consistent effect on nutritional status in regard to manganese. Differences in dietary manganese intake had no consistent effect on indices of manganese or iron status, possibly because foods that contain significant amounts of manganese (green vegetables, breads, and cereals) often contain significant amounts of nonheme iron. Thus, increasing dietary manganese intake by consuming these foods is apt to have limited impact on manganese status because of the interaction between nonheme iron and manganese.
对47名食用典型饮食的女性，研究了血红素铁、非血红素铁和锰的膳食摄入量与锰相关的血液学和营养状况指标之间的关系。通过在饮食中摄入更多非血红素铁来增加膳食铁摄入量，对血液学状况（血细胞比容值、铁蛋白和转铁蛋白浓度）的影响存疑，且对锰相关的营养状况（血清锰、尿锰和淋巴细胞锰依赖性超氧化物歧化酶活性）有负面影响。相比之下，血红素铁摄入量与血液学状况呈正相关，对锰相关的营养状况没有一致的影响。膳食锰摄入量的差异对锰或铁状况指标没有一致的影响，这可能是因为含有大量锰的食物（绿色蔬菜、面包和谷物）通常也含有大量非血红素铁。因此，由于非血红素铁和锰之间的相互作用，通过食用这些食物来增加膳食锰摄入量对锰状况的影响可能有限。
