Wray V, Wagner K G
Z Naturforsch C Biosci. 1977 May-Jun;32(5-6):315-20. doi: 10.1515/znc-1977-5-601.
Complex formation between 5'-adenosine monophosphate (5'-AMP) and tryptamine was investigated by measuring 13C chemical shifts and spin-lattice relaxation times. The chemical shift changes observed were attributed to ring current effects originating in the stacking of the two respective aromatic moieties and to puckering changes of the AMP ribose. Differences in the magnitude of the shifts of the aromatic carbons were related to the geometry of the complex and compared with those found for AMP selfassociation. Upon complex formation the relaxation times of especially the tryptamine indole carbons were greatly reduced, this was explained by an increase in the particle size. Small changes found for the AMP carbons in solutions without tryptamine result from AMP selfassociation. Deviations from isotropic motion observed for the non-aromatic moieties are discussed.
通过测量13C化学位移和自旋晶格弛豫时间，研究了5'-单磷酸腺苷（5'-AMP）与色胺之间的复合物形成。观察到的化学位移变化归因于两个各自芳香部分堆积产生的环电流效应以及AMP核糖的褶皱变化。芳香族碳的位移大小差异与复合物的几何形状有关，并与AMP自缔合的情况进行了比较。形成复合物后，尤其是色胺吲哚碳的弛豫时间大大缩短，这可以通过粒径增加来解释。在没有色胺的溶液中，AMP碳的微小变化是由AMP自缔合引起的。讨论了非芳香部分观察到的各向同性运动偏差。
