Blinder K J, Peyman G A, Desai U R, Nelson N C, Alturki W, Paris C L
Louisiana State University Medical Center School of Medicine, New Orleans 70112.
Br J Ophthalmol. 1992 Sep;76(9):525-8. doi: 10.1136/bjo.76.9.525.
This investigation of the liquid perfluorocarbon, perfluorophenanthrene (Vitreon), establishes its safety and efficacy as a short-term vitreoretinal tamponade. We utilised Vitreon as an intraoperative tool and postoperative vitreoretinal tamponade in 16 patients. Proliferative vitreoretinopathy (PVR) (six), giant retinal tear (four), rhegmatogenous retinal detachment (three), retinal detachment with keratoprosthesis (two), and submacular and vitreous haemorrhage (one) were successfully repaired. Vitreon was left in the eye and removed 5 days to 4 weeks postoperatively. Complications encountered included proliferative PVR (five), limited peripheral retinal detachment (three), macular pucker (two) cataract (three), hypotony (two), excessive fibrin reaction (one), and elevated intraocular pressure (one). At the latest evaluation, all retinas are attached with a follow-up of 1.25 to 12 months (mean 6.8 months).
本次对液态全氟碳化合物全氟菲(Vitreon)的研究证实了其作为短期玻璃体视网膜填塞物的安全性和有效性。我们在16例患者中使用Vitreon作为术中工具和术后玻璃体视网膜填塞物。增殖性玻璃体视网膜病变(PVR)(6例)、巨大视网膜裂孔(4例)、孔源性视网膜脱离(3例)、带角膜移植片的视网膜脱离(2例)以及黄斑下和玻璃体出血(1例)均成功修复。Vitreon留在眼内,术后5天至4周取出。遇到的并发症包括增殖性PVR(5例)、局限性周边视网膜脱离(3例)、黄斑皱襞(2例)、白内障(3例)、低眼压(2例)、纤维蛋白反应过度(1例)以及眼压升高(1例)。在最近一次评估时,所有视网膜均在位,随访时间为1.25至12个月(平均6.8个月)。