维特龙，一种新型全氟碳化合物。
Vitreon, a new perfluorocarbon.
作者信息
Blinder K J, Peyman G A, Paris C L, Dailey J P, Alturki W, Lui K R, Gremillion C M, Clark L C
机构信息
LSU Eye Center, School of Medicine, New Orleans 70112.
出版信息
Br J Ophthalmol. 1991 Apr;75(4):240-4. doi: 10.1136/bjo.75.4.240.
We evaluated a new liquid perfluorocarbon, perfluorophenanthrene (Vitreon). This material has proven to be non-toxic in vitrectomised rabbit eyes for up to six weeks. Present investigation under FDA guidelines establishes both the safety and efficacy of Vitreon in human eyes. We used Vitreon for intraoperative hydrokinetic retinal manipulation in 15 patients. In cases of proliferative vitreoretinopathy (6), rhegmatogenous retinal detachment (5), giant retinal tear (2), retinal dialysis (1), and tractional retinal detachment (1) the retina was successfully reattached. Postoperatively two patients developed proliferative vitreoretinopathy necessitating further surgery, and one patient developed hypotony. Follow-up showed 100% reattachment rate with a mean duration of 6.3 months. Postoperative visual acuity ranges from light perception to 20/30.
我们评估了一种新型液态全氟碳化合物——全氟菲（Vitreon）。这种材料已被证实在兔眼玻璃体切除术后长达六周内无毒。目前根据美国食品药品监督管理局（FDA）的指导方针进行的研究确定了Vitreon在人眼中的安全性和有效性。我们在15例患者的术中视网膜水动力学操作中使用了Vitreon。在增生性玻璃体视网膜病变（6例）、孔源性视网膜脱离（5例）、巨大视网膜裂孔（2例）、视网膜脱离（1例）和牵引性视网膜脱离（1例）的病例中，视网膜成功复位。术后有2例患者发生增生性玻璃体视网膜病变，需要进一步手术，1例患者发生低眼压。随访显示视网膜复位率为100%，平均持续时间为6.3个月。术后视力范围从光感至20/30。
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