Barzen G, Felix R
Strahlenklinik und Poliklinik, Universitätsklinikum Rudolf Virchow, Berlin.
Aktuelle Radiol. 1992 Sep;2(5):262-70.
Radioimmunoscintigraphy (RIS) of colorectal carcinomas is under investigation in controlled clinical studies in Germany since 1985. With the availability of 99mTc labelled monoclonal antibodies against the carcinoembryonic antigen (CEA), there is an increasing acceptance of this new technique; nevertheless, the merits of RIS in comparison to established methods of staging and restaging of patients with colorectal carcinomas as computed tomography, endoscopy and sonography are still under discussion. In this review the current "State of the Art" of radioimmunoscintigraphy of colorectal carcinomas is given in respect of whether there is additional information which can be gained only by Ris but not by the established diagnostic procedure.
自1985年以来，德国一直在对照临床研究中对结直肠癌的放射免疫闪烁显像（RIS）进行研究。随着针对癌胚抗原（CEA）的99mTc标记单克隆抗体的问世，这项新技术越来越被人们所接受；然而，与计算机断层扫描、内窥镜检查和超声检查等结直肠癌患者分期及再分期的既定方法相比，RIS的优点仍在讨论之中。在这篇综述中，就结直肠癌放射免疫闪烁显像是否能提供仅通过RIS而非既定诊断程序才能获得的额外信息，给出了当前的“技术现状”。
