Kapasi A A, Mandrekar P S, D'Cruz A K, Vyas J J, Sheth N A
Endocrinology Unit, Tata Memorial Centre, Parel, Bombay, India.
Cell Biol Int Rep. 1992 Sep;16(9):859-69. doi: 10.1016/s0309-1651(06)80166-9.
We have previously reported the occurrence of inhibin-like peptide in gastric juice of normal men. In the present investigation, normal gastric mucosa was shown to synthesize inhibin, in vitro, as measured by 3H-leucine incorporation (Maximum at 18 h). Furthermore, the immunohistochemical localization studies demonstrated its presence in the acid secreting parietal cells and basal region of foveolar epithelium of gastric mucosa. Surprisingly, the protein secreting zymogen cells remained unstained.
我们之前曾报道过正常男性胃液中存在抑制素样肽。在本研究中,通过³H-亮氨酸掺入法(18小时时达到最大值)测定,显示正常胃黏膜在体外能合成抑制素。此外,免疫组织化学定位研究表明其存在于胃黏膜的泌酸壁细胞和小凹上皮的基底部区域。令人惊讶的是,分泌蛋白质的酶原细胞未被染色。