Johnston B T, Collins B J, Collins J S, Ferguson W R
Royal Victoria Hospital, Belfast, United Kingdom.
Dysphagia. 1992;7(4):201-4. doi: 10.1007/BF02493470.
Sixteen patients (nine male) underwent perendoscopic pneumatic dilatation for achalasia. The Witzel dilator was chosen as it allows placement of the balloon under endoscopic vision. Its efficacy was assessed using esophageal scintigraphy. Symptom score and esophageal transit values at 100 s and after a drink of water all improved significantly (P less than or equal to 0.014) after dilatation and there was a significant correlation between the improved symptom score and the change in transit values after 100 s (r = 0.586, P = 0.017). At follow-up at 8 (3-16) months [mean (range)], 15 of 16 patients (94%) are symptom free. The Witzel dilator is effective in the treatment of achalasia. Esophageal scintigraphy offers a quantitative assessment of esophageal function, helping the clinical investigator evaluate new forms of therapy.
16例患者（9例男性）因贲门失弛缓症接受了经内镜气囊扩张术。选用维泽尔扩张器是因为它能在内镜直视下放置气囊。采用食管闪烁扫描评估其疗效。扩张术后，症状评分、100秒时的食管通过值以及饮水后的食管通过值均显著改善（P≤0.014），且改善后的症状评分与100秒后通过值的变化之间存在显著相关性（r = 0.586，P = 0.017）。在8（3 - 16）个月[平均（范围）]的随访中，16例患者中有15例（94%）无症状。维泽尔扩张器治疗贲门失弛缓症有效。食管闪烁扫描可对食管功能进行定量评估，有助于临床研究人员评估新的治疗方法。
