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抗坏血酸对豚鼠组织中镉蓄积的影响。

The effect of ascorbic acid on cadmium accumulation in guinea pig tissues.

作者信息

Kadrabová J, Madăric A, Ginter E

机构信息

Institute of Preventive and Clinical Medicine, Bratislava, Czecho-Slovakia.

出版信息

Experientia. 1992 Oct 15;48(10):989-91. doi: 10.1007/BF01919148.

DOI:10.1007/BF01919148
PMID:1426151
Abstract

Accumulation of cadmium in organs of guinea pigs after subchronic oral cadmium treatment (1 mg Cd/animal/24 h) was in the following order: kidneys > liver > heart > testes > brain. The preventive effects of high doses of ascorbic acid (AA) against cadmium deposition were more pronounced in the testes, heart and brain, and in the kidney only after short-term cadmium treatment. Ascorbic acid had no protective effect on cadmium accumulation in the liver.

摘要

在亚慢性口服镉处理(每只动物每天1毫克镉)后,豚鼠器官中镉的蓄积顺序如下:肾脏>肝脏>心脏>睾丸>大脑。高剂量抗坏血酸(AA)对镉沉积的预防作用在睾丸、心脏和大脑中更为明显,仅在短期镉处理后对肾脏有明显作用。抗坏血酸对肝脏中镉的蓄积没有保护作用。

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本文引用的文献

1
Acute exposure to cadmium causes severe liver injury in rats.急性接触镉会导致大鼠严重肝损伤。
Toxicol Appl Pharmacol. 1982 Sep 15;65(2):302-13. doi: 10.1016/0041-008x(82)90013-8.
2
Effects of vitamin C and iron and cadmium metabolism.维生素C对铁和镉代谢的影响。
Ann N Y Acad Sci. 1980;355:249-61. doi: 10.1111/j.1749-6632.1980.tb21343.x.
3
Recent progress and perspectives in cadmium health effects studies.镉对健康影响的研究进展与展望
Cell Biol Toxicol. 1994 Feb;10(1):1-22. doi: 10.1007/BF00757183.
Sci Total Environ. 1980 Apr;14(3):199-232. doi: 10.1016/0048-9697(80)90024-8.
4
Effects of dietary mineral levels on metabolism and requirements.
Neurotoxicology. 1983 Fall;4(3):113-20.
5
Effect of ascorbic acid on cadmium toxicity in the young coturnix.抗坏血酸对雏鹌鹑镉毒性的影响。
J Nutr. 1971 Oct;101(10):1295-305. doi: 10.1093/jn/101.10.1295.
6
Applications of a slotted quartz tube and flame atomic-absorption spectrometry to the analysis of biological samples.开槽石英管与火焰原子吸收光谱法在生物样品分析中的应用。
Analyst. 1985 Jun;110(6):579-82. doi: 10.1039/an9851000579.
7
Prevalence of hypertension among cadmium-exposed workers.镉暴露工人中高血压的患病率。
Arch Environ Health. 1985 May-Jun;40(3):185-90. doi: 10.1080/00039896.1985.10545915.
8
Induced synthesis of metallothionein by ascorbic acid in mouse liver.抗坏血酸诱导小鼠肝脏金属硫蛋白的合成。
Toxicology. 1987 Mar;43(3):251-9. doi: 10.1016/0300-483x(87)90084-9.
9
Pulmonary cadmium oxide toxicity in the rat.大鼠肺氧化镉毒性
J Toxicol Environ Health. 1987;21(1-2):233-50. doi: 10.1080/15287398709531015.
10
Metallothionein.金属硫蛋白
Annu Rev Biochem. 1986;55:913-51. doi: 10.1146/annurev.bi.55.070186.004405.