抗坏血酸对豚鼠组织中镉蓄积的影响。
The effect of ascorbic acid on cadmium accumulation in guinea pig tissues.
作者信息
Kadrabová J, Madăric A, Ginter E
机构信息
Institute of Preventive and Clinical Medicine, Bratislava, Czecho-Slovakia.
出版信息
Experientia. 1992 Oct 15;48(10):989-91. doi: 10.1007/BF01919148.
PMID:1426151
Abstract
Accumulation of cadmium in organs of guinea pigs after subchronic oral cadmium treatment (1 mg Cd/animal/24 h) was in the following order: kidneys > liver > heart > testes > brain. The preventive effects of high doses of ascorbic acid (AA) against cadmium deposition were more pronounced in the testes, heart and brain, and in the kidney only after short-term cadmium treatment. Ascorbic acid had no protective effect on cadmium accumulation in the liver.
摘要
在亚慢性口服镉处理（每只动物每天1毫克镉）后，豚鼠器官中镉的蓄积顺序如下：肾脏＞肝脏＞心脏＞睾丸＞大脑。高剂量抗坏血酸（AA）对镉沉积的预防作用在睾丸、心脏和大脑中更为明显，仅在短期镉处理后对肾脏有明显作用。抗坏血酸对肝脏中镉的蓄积没有保护作用。
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