补充抗坏血酸对吸烟者精子质量的影响。
Effect of ascorbic acid supplementation on the sperm quality of smokers.
作者信息
Dawson E B, Harris W A, Teter M C, Powell L C
机构信息
Department of Obstetrics and Gynecology, University of Texas Medical Branch, Galveston 77555.
出版信息
Fertil Steril. 1992 Nov;58(5):1034-9.
OBJECTIVE
To determine the effect of ascorbic acid supplementation on the sperm quality of heavy smokers.
DESIGN
Microscopic examination of semen for 1 month during supplementation with placebo or ascorbic acid at dose levels of 200 or 1,000 mg/d.
SETTING
Department of Obstetrics and Gynecology, The University of Texas Medical Branch.
PARTICIPANTS
Seventy-five men (20 to 35 years old) randomly divided into one of three supplementation groups: placebo, 200 mg and 1,000 mg of ascorbic acid.
MAIN OUTCOME
Improvement in sperm quality as compared with presupplementation levels and between the three treatment groups.
RESULTS
The placebo group showed no improvement in sperm quality. The groups receiving ascorbic acid showed improvement in sperm quality with most improvement in the 1,000-mg group. Pearson's correlation showed statistically significant relationships between the weekly group means of serum and seminal plasma ascorbic acid levels and sperm qualities.
CONCLUSIONS
Ascorbic acid supplementation of heavy smokers in excess of 200 mg/d results in improved sperm quality.
目的
确定补充维生素C对重度吸烟者精子质量的影响。
设计
在补充安慰剂或剂量为200毫克/天或1000毫克/天的维生素C期间，对精液进行为期1个月的显微镜检查。
地点
德克萨斯大学医学分部妇产科。
参与者
75名年龄在20至35岁之间的男性，随机分为三个补充组之一：安慰剂组、200毫克维生素C组和1000毫克维生素C组。
主要结果
与补充前水平以及三个治疗组之间相比，精子质量的改善情况。
结果
安慰剂组精子质量没有改善。接受维生素C的组精子质量有所改善，1000毫克组改善最为明显。Pearson相关性分析显示，血清和精浆中维生素C水平的每周组均值与精子质量之间存在统计学上的显著关系。
结论
重度吸烟者每天补充超过200毫克的维生素C可改善精子质量。
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