单纯疱疹病毒和巨细胞病毒的热灭活
THERMOINACTIVATION OF HERPES SIMPLEX VIRUS AND CYTOMEGALOVIRUS.
作者信息
PLUMMER G, LEWIS B
出版信息
J Bacteriol. 1965 Mar;89(3):671-4. doi: 10.1128/jb.89.3.671-674.1965.
Plummer, Gordon (Baylor University College of Medicine, Houston, Tex.), and Brian Lewis. Thermoinactivation of herpes simplex virus and cytomegalovirus. J. Bacteriol. 89:671-674. 1965.-The stability of herpes simplex virus and of human cytomegalovirus at 4, 22, 36, and 50 C was studied. A plateau or lag phase, during which no loss of viability was detected, was a constant feature of the inactivation curves of herpesvirus and cytomegalovirus at 36 and 22 C and of herpesvirus at 4 C. Unlike herpesvirus, cytomegalovirus was repeatedly found to be less stable at 4 C (and at 10 C) than at room temperature (22 C). Extracellular herpesvirus harvested from the supernatant culture fluid seemed to be more stable than intracellular virus obtained by sonic disintegration of the infected cells. Serum had a stabilizing effect at 36 C on both intracellular and extracellular virus.
普拉默，戈登（得克萨斯州休斯敦贝勒医学院），以及布莱恩·刘易斯。单纯疱疹病毒和巨细胞病毒的热灭活。《细菌学杂志》89:671 - 674。1965年。——研究了单纯疱疹病毒和人巨细胞病毒在4℃、22℃、36℃和50℃下的稳定性。在36℃和22℃时疱疹病毒以及在4℃时疱疹病毒的灭活曲线都有一个平稳期或滞后期，在此期间未检测到活力丧失，这是一个恒定特征。与疱疹病毒不同，巨细胞病毒在4℃（以及10℃）时反复被发现比在室温（22℃）时更不稳定。从上清培养液中收获的细胞外疱疹病毒似乎比通过感染细胞超声破碎获得的细胞内病毒更稳定。血清在36℃时对细胞内和细胞外病毒都有稳定作用。
Zotero 插件