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Repressible and inducible enzymic forms of dimethylnitrosamine-demethylase.

作者信息

Arcos J C, Davies D L, Brown C E, Argus M F

出版信息

Z Krebsforsch Klin Onkol Cancer Res Clin Oncol. 1977 Jun 27;89(2):181-99. doi: 10.1007/BF00308517.

DOI:10.1007/BF00308517
PMID:143144
Abstract
摘要

相似文献

1
Repressible and inducible enzymic forms of dimethylnitrosamine-demethylase.二甲基亚硝胺脱甲基酶的可阻遏型和诱导型酶形式。
Z Krebsforsch Klin Onkol Cancer Res Clin Oncol. 1977 Jun 27;89(2):181-99. doi: 10.1007/BF00308517.
2
Effect of polychlorinated biphenyls (Aroclor 1254) on inducible and repressible microsomal N-demethylases in the mouse and rat.多氯联苯（Aroclor 1254）对小鼠和大鼠体内诱导性和可抑制性微粒体N-脱甲基酶的影响。
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3
Induction of dimethylnitrosamine demethylase activity in mouse liver by polychlorinated biphenyls and 3-methylcholanthrene.多氯联苯和3-甲基胆蒽对小鼠肝脏中二甲基亚硝胺脱甲基酶活性的诱导作用。
Biochem Pharmacol. 1980 May 15;29(10):1375-83. doi: 10.1016/0006-2952(80)90433-5.
4
Studies on the metabolism of dimethylnitrosamine in the rat. II. The effects of phenobarbitone and 20-methylcholanthrene on the in vitro and in vivo metabolism and acute toxicity of dimethylnitrosamine in young and mature rats.
Food Cosmet Toxicol. 1975 Dec;13(6):611-7. doi: 10.1016/0015-6264(75)90150-9.
5
Dimethylnitrosamine-demethylase: absence of increased enzyme catabolism and multiplicity of effector sites in repression. Hemoprotein involvement.二甲基亚硝胺脱甲基酶：酶分解代谢未增加及阻遏中效应位点的多样性。含血红素蛋白的参与。
Chem Biol Interact. 1976 May;13(2):127-40. doi: 10.1016/0009-2797(76)90002-8.
6
Induction of hepatic mono-oxygenase systems of pregnant rats with phenobarbital and 3-methylcholanthrene.用苯巴比妥和3-甲基胆蒽诱导妊娠大鼠肝脏单加氧酶系统
Biochem Pharmacol. 1977 Apr 1;26(7):577-84. doi: 10.1016/0006-2952(77)90027-2.
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Inhibition of rat hepatic dimethylnitrosamine demethylase by cyclic and acyclic nitrosamines and secondary amines.环状及非环状亚硝胺和仲胺对大鼠肝脏二甲基亚硝胺脱甲基酶的抑制作用。
Experientia. 1978 Nov 15;34(11):1505-6. doi: 10.1007/BF01932378.
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Effects of cytochrome p-448 and p-450 inducers on microsomal dimethylnitrosamine demethylase activity and the capacity of isolated microsomes to activate dimethylnitrosamine to a mutagen.细胞色素P - 448和P - 450诱导剂对微粒体二甲基亚硝胺脱甲基酶活性以及分离的微粒体将二甲基亚硝胺激活为诱变剂能力的影响。
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No neoplastic alteration of metabolically competent rat liver cells in vitro by chemical carcinogens: 3-methylcholanthrene, dimethylnitrosamine and Natulan.化学致癌物3-甲基胆蒽、二甲基亚硝胺和丙卡巴肼在体外不会引起具有代谢活性的大鼠肝细胞发生肿瘤性改变。
Cancer Biochem Biophys. 1978;3(1):1-6.
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Factors affecting the induction of dimethylnitrosamine demethylase by Aroclor 1254.影响Aroclor 1254诱导二甲基亚硝胺去甲基酶的因素。
Cancer Res. 1977 Jan;37(1):329-30.

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2
Effect of ethanol on microsomal metabolism of dimethylnitrosamine.乙醇对二甲基亚硝胺微粒体代谢的影响。
J Cancer Res Clin Oncol. 1980;97(3):233-40. doi: 10.1007/BF00405774.
3
Evolution of activation-detoxification enzyme patterns during precarcinogenesis in synergism: 3-methylcholanthrene and dimethylnitrosamine.协同作用下致癌前阶段激活 - 解毒酶模式的演变：3 - 甲基胆蒽与二甲基亚硝胺

本文引用的文献

1
Protein measurement with the Folin phenol reagent.使用福林酚试剂进行蛋白质测定。
J Biol Chem. 1951 Nov;193(1):265-75.
2
[Inhibitory action of aminoacetonitrile of hydropic degeneration and necrosis induced by chloroform in the rat liver and kidney].[氨基乙腈对氯仿诱导的大鼠肝和肾水样变性及坏死的抑制作用]
Sperimentale. 1962 Sep-Oct;112:365-75.
3
Induction of microsomal enzyme synthesis by polycyclic aromatic hydrocarbons of different molecular sizes.不同分子大小的多环芳烃对微粒体酶合成的诱导作用。
J Cancer Res Clin Oncol. 1982;103(3):227-40. doi: 10.1007/BF00409699.
4
Further studies on dimethylnitrosamine metabolism, activation and its ability to cause liver injury.关于二甲基亚硝胺代谢、活化及其致肝损伤能力的进一步研究。
Arch Toxicol. 1981 Jun;47(3):159-68. doi: 10.1007/BF00368676.
5
Influence of a prolonged treatment with disulfiram and D(-)penicillamine on nitrosodiethylamine-induced biological and biochemical effects in rats. I. Investigations on the drug metabolizing system.双硫仑和D(-)青霉胺长期治疗对大鼠亚硝基二乙胺诱导的生物学和生化效应的影响。I. 对药物代谢系统的研究。
J Cancer Res Clin Oncol. 1985;109(1):9-15. doi: 10.1007/BF01884248.
6
Passively inhaled tobacco smoke: a challenge to toxicology and preventive medicine.被动吸入的烟草烟雾：对毒理学和预防医学的一项挑战。
Arch Toxicol. 1987 Dec;61(2):89-104. doi: 10.1007/BF00661366.
J Biol Chem. 1961 May;236:1291-6.
4
Graphical analysis of single enzyme systems.单一酶系统的图形分析。
Enzymologia. 1956 Jul 15;17(5-6):273-8.
5
Studies on the denaturation of biological macromolecules by chemical carcinogens. I. Aggregation, viscosity and optical rotation changes produced in ovalbumin by nitrosamines and other water-soluble carcinogens.
Arzneimittelforschung. 1966 Jun;16(6):740-6.
6
Studies on the denaturation of biological macromolecules by chemical carcinogens. 3. Optical rotatory dispersion and light-scattering changes of ovalbumin during denaturation and aggregation by water-soluble carcinogens.化学致癌物对生物大分子的变性作用研究。3. 水溶性致癌物使卵清蛋白变性和聚集过程中的旋光色散及光散射变化
Biochim Biophys Acta. 1966 Oct 10;126(2):274-85. doi: 10.1016/0926-6585(66)90064-1.
7
Combined carcinogenic effects of dimethylnitrosamine and 3-methylcholanthrene in the rat.二甲基亚硝胺与3-甲基胆蒽对大鼠的联合致癌作用。
J Natl Cancer Inst. 1968 Mar;40(3):535-49.
8
The effect of cobalt chloride administration on the synthesis of hepatic microsomal cytochrome P-450.氯化钴给药对肝微粒体细胞色素P-450合成的影响。
Biochem Biophys Res Commun. 1971 Feb 19;42(4):589-95. doi: 10.1016/0006-291x(71)90528-6.
9
Amino acid induction and carbohydrate repression of dimethylnitrosamine demethylase in rat liver.大鼠肝脏中二甲基亚硝胺脱甲基酶的氨基酸诱导及碳水化合物阻遏作用
Cancer Res. 1970 Oct;30(10):2563-7.
10
Mechanism of 3-methylcholanthrene-induced inhibition of dimethylnitrosamine demethylase in rat liver.3-甲基胆蒽诱导大鼠肝脏中二甲基亚硝胺脱甲基酶抑制的机制。
Cancer Res. 1970 Oct;30(10):2556-62.