Loubatières-Mariani M M, Chapal J, Puech R, Loubatières A
C R Seances Soc Biol Fil. 1977;171(1):165-8.
In the presence of a glucose concentration of 1.5 g/1 the secretion of insulin from the isolated perfused rat pancreas is clearly weaker at 28 degrees C than at 37.5 degrees C. In response to cholinergic stimulation, the absolute increase of insulin secretion rate is less at 28 degrees C than at 37.5 degrees C. However, when evaluated in percentage in relation to the baseline value, this increase is more important at the lower temperature. As to glucagon secretion, lowering of the temperature from 37.5 degrees C to 28 degrees C modifies neither this secretion in the presence of glucose alone, nor the increased secretion provoked by the cholinergic stimulation.
在葡萄糖浓度为1.5克/升的情况下，在28摄氏度时，从分离的灌注大鼠胰腺分泌的胰岛素明显比在37.5摄氏度时弱。对胆碱能刺激的反应是，在28摄氏度时胰岛素分泌率的绝对增加量比在37.5摄氏度时少。然而，当相对于基线值以百分比进行评估时，在较低温度下这种增加更为显著。至于胰高血糖素分泌，将温度从37.5摄氏度降至28摄氏度，既不会改变仅存在葡萄糖时的这种分泌，也不会改变由胆碱能刺激引起的分泌增加。
