膜中伴随加速氧传输的张力梯度

TENSION GRADIENTS ACCOMPANYING ACCELERATED OXYGEN TRANSPORT IN A MEMBRANE.

作者信息

SCHOLANDER P F

出版信息

Science. 1965 Aug 20;149(3686):876-7. doi: 10.1126/science.149.3686.876.

DOI:10.1126/science.149.3686.876

Abstract

Facilitated transport of oxygen through hemoglobin has been studied by use of a membrane sandwich of hemoglobin, Teflon, and water. Transport is enhanced only when there is a hemoglobin-bound-0(2) gradient in the pigment. When passing through a fully oxygenated layer, the accelerated transport is carried by an increased diffusion gradient of oxygen pressure through the solvent. The results substantiate experimentally the diffusion gradients proposed by Zilversmit.

摘要

通过使用血红蛋白、聚四氟乙烯和水的膜夹层来研究血红蛋白促进氧气运输的情况。只有当色素中存在与血红蛋白结合的氧梯度时，运输才会增强。当通过完全氧化的层时，加速运输是由通过溶剂的氧分压扩散梯度增加来实现的。这些结果通过实验证实了齐尔弗斯米特提出的扩散梯度。