Cáceres A, Saravia A, Rizzo S, Zabala L, De Leon E, Nave F
Center for Mesoamerican Studies on Appropriate Technology (CEMAT), Guatemala City, Guatemala.
J Ethnopharmacol. 1992 Jun;36(3):233-7. doi: 10.1016/0378-8741(92)90049-w.
Hot water infusions of flowers, leaves, roots, seeds and stalks or bark of Moringa oleifera were screened to detect three pharmacologic activities in experimental models in rats. The antispasmodic activity was demonstrated using isolated duodenum, oral anti-inflammatory activity by carrageenan-induced hindpaw edema and oral diuretic activity by urine output in metabolic cages. The seed infusion showed a significant inhibition of acetylcholine-induced contraction with an ED50 of 65.6 mg/ml bath concentration, inhibition of carrageenan-induced edema at 1000 mg/kg and diuretic activity at 1000 mg/kg. Some activity was also demonstrated in the roots. All doses expressed here are as equivalents of dried starting plant material.
对辣木的花、叶、根、种子、茎或树皮的热水浸剂进行了筛选，以在大鼠实验模型中检测三种药理活性。使用离体十二指肠证明其具有解痉活性，通过角叉菜胶诱导的后爪水肿证明其具有口服抗炎活性，通过代谢笼中的尿量证明其具有口服利尿活性。种子浸剂显示出对乙酰胆碱诱导的收缩有显著抑制作用，浴液浓度的半数有效剂量（ED50）为65.6毫克/毫升，在1000毫克/千克时对角叉菜胶诱导的水肿有抑制作用，在1000毫克/千克时有利尿活性。根中也显示出一些活性。此处给出的所有剂量均以干燥起始植物材料的等效量表示。
