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对单个分离的跳动心脏细胞的体外研究。

In vitro studies of single isolated beating heart cells.

作者信息

HARARY I, FARLEY B

出版信息

Science. 1960 Jun 3;131(3414):1674-5. doi: 10.1126/science.131.3414.1674.

DOI:10.1126/science.131.3414.1674
PMID:14399673
Abstract

Rat heart cells, separated by trypsin treatment and grown attached to glass in a liquid medium, exhibit periodic contractions similar to a whole beating heart. The rate of beating, which is up to 150 beats per minute, is affected by cardiac drugs and by metabolic substrates and inhibitors.

摘要

通过胰蛋白酶处理分离出来并附着在玻璃上于液体培养基中生长的大鼠心脏细胞，呈现出与完整跳动心脏相似的周期性收缩。其跳动速率可达每分钟150次，会受到心脏药物、代谢底物及抑制剂的影响。

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