Skinner W S, Dennis P A, Li J P, Quistad G B
Sandoz Agro, Inc., Research Division, Palo Alto, CA 94304.
Toxicon. 1992 Sep;30(9):1043-50. doi: 10.1016/0041-0101(92)90049-b.
Nine insecticidal peptides were isolated from the venom of the trap-door spider, Aptostichus schlingeri. Seven of these toxins cause flaccid paralysis of insect larvae within 10 min of injection and all were lethal within 24 hr. The complete amino acid sequences (32-76 residues) of six peptides are presented. The identified peptides contain three or four disulfide bonds and the larger peptides (74-76 residues) are quite similar in sequence with carboxyl termini as free acids, not amidated.
从活板门蛛Aptostichus schlingeri的毒液中分离出了九种杀虫肽。其中七种毒素在注射后10分钟内可导致昆虫幼虫弛缓性麻痹，且在24小时内全部致死。本文给出了六种肽的完整氨基酸序列（32 - 76个残基）。鉴定出的肽含有三个或四个二硫键，较大的肽（74 - 76个残基）在序列上非常相似，其羧基末端为游离酸，而非酰胺化形式。
