Leggatt G R, Yang W, McManus D P
Tropical Health Program, Queensland Institute of Medical Research, Bancroft Centre, Brisbane, Australia.
Trans R Soc Trop Med Hyg. 1992 Mar-Apr;86(2):189-92. doi: 10.1016/0035-9203(92)90566-u.
This study evaluated the 12 kDa (smallest) subunit of Echinococcus granulosus antigen B as a diagnostic molecule. Using immunoblotting, 90.9% of cystic hydatid patients, 40% of alveolar hydatid patients and 5.5% of cysticercosis patients showed sero-reactivity to this subunit. Human antibody response to the 12 kDa molecule appeared independent of factors such as parasite strain or host population responsiveness. The majority of infection sera, and some normal human controls, also recognized the 38 kDa subunit of antigen 5.
本研究评估了细粒棘球绦虫抗原B的12 kDa（最小）亚基作为一种诊断分子的情况。通过免疫印迹法，90.9%的囊型包虫病患者、40%的泡型包虫病患者和5.5%的囊尾蚴病患者对此亚基表现出血清反应性。人类对12 kDa分子的抗体反应似乎独立于诸如寄生虫株或宿主群体反应性等因素。大多数感染血清以及一些正常人类对照也识别抗原5的38 kDa亚基。
