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[双核T淋巴细胞中的微核检测。100名受试者群体中分布及变异因素分析]

[Assay of micronuclei in binucleated T-lymphocytes. Analysis of the distribution and variation factors in a population of 100 subjects].

作者信息

Di Giorgio C, Botta A, De Meo M P, Laget M, Dumenil G

机构信息

Laboratoire de biogénotoxicologie, faculté de médecine, Marseille, France.

出版信息

Ann Biol Clin (Paris). 1992;50(1):21-4.

PMID:1443786
Abstract

The authors analysed micronuclei levels distribution in lymphocytes of 100 non occupationally exposed subjects and studied the effect of age, sex and smoking of donors on the distribution. Results showed that micronucleated cells were distributed according to a normal distribution (average = 9.5 +/- 4 micronucleated cells in 1,000 binucleated lymphocytes). Age and sex of donors had no effect on the distribution but, concerning smoking, the results showed that micronuclei levels were correlated to the number of cigarettes daily smoked.

摘要

作者分析了100名非职业暴露受试者淋巴细胞中的微核水平分布,并研究了供体的年龄、性别和吸烟情况对该分布的影响。结果显示,微核化细胞呈正态分布(每1000个双核淋巴细胞中平均有9.5±4个微核化细胞)。供体的年龄和性别对分布没有影响,但关于吸烟,结果表明微核水平与每日吸烟量相关。

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