Miyamoto Y, Morishita Y, Ohwada S, Nakamura S, Takeyoshi I, Tanahashi Y, Kusaba T, Usui R, Minaguchi S, Shiozaki H
2nd Department of Surgery, Gunma University School of Medicine, Maebashi, Japan.
Gan To Kagaku Ryoho. 1992 Nov;19(13):2195-9.
This study was undertaken in order to evaluate the effect of intraperitoneal administration of CDDP on fourteen patients with peritoneal dissemination of advanced or recurrent gastric cancer. The procedure was used together specific hydration transfusion and diuretics. Two patients showed a complete response and 5 patients a partial response. Following this therapy, 2 patients have survived for more than 6 months. Alimentary symptoms (nausea, vomiting) were found but renal toxicity and serious myelosuppression were not recognized in all patients.
本研究旨在评估腹腔内给予顺铂对14例晚期或复发性胃癌腹膜转移患者的疗效。该程序与特定的水化输液和利尿剂一起使用。2例患者完全缓解，5例患者部分缓解。经过这种治疗，2例患者存活超过6个月。发现有消化道症状（恶心、呕吐），但并非所有患者都出现肾毒性和严重的骨髓抑制。
