Kaye B R, Neuwelt C M, London S S, DeArmond S J
East Bay Rheumatology Medical Group, Oakland, CA.
Ann Rheum Dis. 1992 Oct;51(10):1152-6. doi: 10.1136/ard.51.10.1152.
The case is reported of a patient with central nervous system systemic lupus erythematosus (SLE) with features of progressive multifocal leucoencephalopathy (PML) seen clinically and by magnetic resonance imaging. A brain biopsy sample showed microinfarcts. The use of magnetic resonance imaging and IgG synthesis rates in evaluating central nervous system lupus, the co-occurrence of SLE and PML, and the differentiation of these entities by magnetic resonance imaging and by histology are considered.
报告了一例患有中枢神经系统系统性红斑狼疮（SLE）的患者，其临床表现和磁共振成像显示具有进行性多灶性白质脑病（PML）的特征。脑活检样本显示有微梗死灶。文中讨论了磁共振成像和IgG合成率在评估中枢神经系统狼疮中的应用、SLE与PML的共存情况，以及通过磁共振成像和组织学对这些疾病进行鉴别诊断的问题。
