Shalev A Y, Orr S P, Peri T, Schreiber S, Pitman R K
Center for Traumatic Stress, Hadassah University Hospital, Jerusalem, Israel.
Arch Gen Psychiatry. 1992 Nov;49(11):870-5. doi: 10.1001/archpsyc.1992.01820110034005.
Orbicularis oculi (eye blink) electromyogram, skin conductance, and heart rate responses to 15 consecutive 95-dB, 500-millisecond, 1000-Hz tones with 0-millisecond rise and fall times were measured in 14 patients with posttraumatic stress disorder, 14 patients with other anxiety disorders, 15 mentally healthy subjects with past traumatic experiences, and 19 mentally healthy subjects with no trauma history. The patients with posttraumatic stress disorder showed significantly larger skin conductance and heart rate responses and a trend toward larger electromyogram responses to the tones than every other group. These effects were not explained by subjective anxiety, resting physiologic arousal, physiologic arousal preceding the tone trials, or initial physiologic responsivity. The group with posttraumatic stress disorder was the only one that failed to show habituation of skin conductance responses.
对14名创伤后应激障碍患者、14名患有其他焦虑症的患者、15名有过创伤经历的心理健康受试者以及19名无创伤史的心理健康受试者,测量了眼轮匝肌(眨眼)肌电图、皮肤电传导和心率对15个连续的95分贝、500毫秒、1000赫兹音调(上升和下降时间均为0毫秒)的反应。创伤后应激障碍患者的皮肤电传导和心率反应显著更大,并且与其他每组相比,对音调的肌电图反应有增大的趋势。这些效应无法用主观焦虑、静息生理唤醒、音调试验前的生理唤醒或初始生理反应性来解释。创伤后应激障碍组是唯一未表现出皮肤电传导反应习惯化的组。