Mishan'kin B N, Aseeva L E, Shevchenko L A, Rublev B D
Biull Eksp Biol Med. 1992 Jun;113(6):629-31.
The effect of purified preparation of adenylate cyclase isolated from Y. pestis on peritoneal leukocytes of white mice and guinea pigs was investigated. Y. pestis adenylate cyclase was shown to accomplish its pathogenic action via histamine-specific receptors on the surface of eukaryotic cells. The involvement of H1 and H2 histamine receptors on target cells in the adenylate cyclase action leading to development of plague infection is discussed.
研究了从鼠疫耶尔森氏菌中分离出的腺苷酸环化酶纯化制剂对小白鼠和豚鼠腹膜白细胞的作用。结果表明，鼠疫耶尔森氏菌腺苷酸环化酶通过真核细胞表面的组胺特异性受体发挥其致病作用。文中讨论了靶细胞上的H1和H2组胺受体在腺苷酸环化酶作用导致鼠疫感染发展过程中的参与情况。
