Aseeva L E, Mishan'kin B N, Shimaniuk N Ia, Rublev B D, Vodop'ianov S O
Mikrobiol Z. 1993 Jun-Aug;55(4):59-63.
Neuraminidase isolated from Yersinia pestis [correction of the plaque microbe] and purified has been studied for its effect on the peritoneal leukocytes of the white mice with results presented. Neuraminidase exerted the insulin-like effect on the peritoneal leukocytes of the white mice and this effect depended on the used dose. The priming of leukocytes by neuraminidase preparation was accompanied by the sharp increase of hydrogen peroxide production under effect of the capsule antigen of the plaque microbe and, apparently, by the appearance of additional binding sites for the adhesion piles of the plaque agent.
对从鼠疫耶尔森菌[对鼠疫杆菌的修正]中分离并纯化得到的神经氨酸酶对小白鼠腹腔白细胞的作用进行了研究，并给出了结果。神经氨酸酶对小白鼠腹腔白细胞具有胰岛素样作用，且该作用取决于所使用的剂量。神经氨酸酶制剂对白细胞的启动作用伴随着在鼠疫杆菌荚膜抗原作用下过氧化氢产生的急剧增加，并且显然伴随着鼠疫杆菌黏附素额外结合位点的出现。
