Sanderson P L, Morris M A, Stanley J K, Fahmy N R
Stockport Infirmary, Cheshire, England.
J Bone Joint Surg Br. 1992 Nov;74(6):923-7. doi: 10.1302/0301-620X.74B6.1447259.
We studied prospectively the relationship between serum lipids and Dupuytren's disease of the hand in 85 patients, 65 men and 20 women. The Dupuytren patients had significantly higher fasting serum cholesterol and triglyceride levels than did the controls (p < 0.001). The raised levels of serum lipids appeared to be associated with the pathogenesis of Dupuytren's disease, and this may help to explain the high incidence of Dupuytren's disease in alcoholic, diabetic and epileptic patients, since these conditions are also associated with raised serum lipid levels.
我们前瞻性地研究了85例患者(65名男性和20名女性)手部掌腱膜挛缩症与血脂之间的关系。掌腱膜挛缩症患者的空腹血清胆固醇和甘油三酯水平显著高于对照组(p < 0.001)。血脂水平升高似乎与掌腱膜挛缩症的发病机制有关,这可能有助于解释酗酒者、糖尿病患者和癫痫患者中掌腱膜挛缩症的高发病率,因为这些病症也与血脂水平升高有关。