Ivey D M, Krulwich T A
Department of Biochemistry, Mount Sinai School of Medicine of CUNY, NY 10029.
Res Microbiol. 1992 Jun;143(5):467-70. doi: 10.1016/0923-2508(92)90092-3.
The a and c subunits of two unrelated alkaliphilic Bacillus species contain unusual motifs in regions previously implicated by others in H(+)-coupled oxidative phosphorylation. The facultative alkaliphile B. firmus OF4 apparently does not contain genes encoding an alternative F0, supporting other evidence that a single species of proton-translocating F1F0-ATPase catalyses oxidative phosphorylation both at low and high pH. The unusual F0 sequence motifs may be part of the adaptation of the extreme alkaliphiles to growth at very high pH.
两种不相关的嗜碱芽孢杆菌的a和c亚基在先前被其他人认为与H⁺偶联氧化磷酸化有关的区域含有不寻常的基序。兼性嗜碱菌坚强芽孢杆菌OF4显然不包含编码替代F0的基因，这支持了其他证据，即单一物种的质子转运F1F0 - ATP酶在低pH和高pH下均催化氧化磷酸化。不寻常的F0序列基序可能是极端嗜碱菌适应在非常高的pH下生长的一部分。
