Matthews Nora S, Hartke Sherrie, Allen John C
Department of Small Animal Medicine and Surgery, Texas A&M University, College Station, TX 77843-4474, USA.
Vet Anaesth Analg. 2003 Jan;30(1):3-14. doi: 10.1046/j.1467-2995.2003.00121.x.
Evaluation of five pulse oximeters in dogs, cats and horses with sensors placed at five sites and hemoglobin saturation at three plateaus.
Prospective randomized multispecies experimental trial.
Five healthy dogs, cats and horses.
Animals were anesthetized and instrumented with ECG leads and arterial catheters. Five pulse oximeters (Nellcor Puritan Bennett-395, NPB-190, NPB-290, NPB-40 and Surgi-Vet V3304) with sensors at five sites were studied in a 5 x 5 Latin square design. Ten readings (SpO2) were taken at each of three hemoglobin saturation plateaus (98, 85 and 72%) in each animal. Arterial samples were drawn concurrently and hemoglobin saturation was measured with a co-oximeter. Accuracy of saturation measurements was calculated as the root mean squared difference (RMSD), a composite of bias and precision, for each model tested in each species.
Accuracy varied widely. In dogs, the RMSD for the NPB-395, NPB-190, NPB-290, NPB-40 and V3304 were 2.7, 2.2, 2.4, 1.7 and 2.7% respectively. Failure to produce readings for the NPB-395, NPB-190, NPB-290, NPB-40 and V3304 were 0, 0, 0.7, 0, and 20%, respectively. The Pearson correlation coefficients for the tongue, toe, ear, lip and prepuce or vulva were 0.95, 0.97, 0.69, 0.87 and 0.95, respectively. In horses, the RMSD for the NPB-395, NPB-190, NPB-290, NPB-40 and V3304 were 3.1, 3.0, 4.7, 3.3 and 2.1%, respectively while rates of failure to produce readings were 10, 21, 0, 17 and 60%, respectively. The Pearson correlation coefficients for the tongue, nostril, ear, lip and prepuce or vulva were 0.98, 0.94, 0.88, 0.93 and 0.94, respectively. In cats, the RMSD for all data for the NPB-395, NPB-190, NPB-290, NPB-40 and V3304 were 5.9, 5.6, 7.9, 7.9 and 10.7%, respectively while failure rates were 0, 0.7, 0, 20 and 32%, respectively. The correlation coefficients for the tongue, rear paw, ear, lip and front paw were 0.54, 0.79,.0.64, 0.49 and 0.57, respectively. For saturations above 90% in cats, the RMSD for the NPB-395, NPB-190, NPB-290, NPB-40 and V3304 were 2.6, 4.4, 4.0, 3.5 and 4.8%, respectively, while failure rates were 0, 1.7, 0, 25 and 43%, respectively.
Accuracy and failure rates (failure to produce a reading) varied widely from model to model and from species to species. Generally, among the models tested in the clinically relevant range (90-100%) RMSD ranged from 2-5% while failure rates were highest in the V3304.
在狗、猫和马身上,将传感器置于五个部位,并在三个饱和度平台下,对五款脉搏血氧仪进行评估。
前瞻性随机多物种实验性试验。
五只健康的狗、猫和马。
对动物实施麻醉,并安装心电图导联和动脉导管。采用5×5拉丁方设计,研究五款脉搏血氧仪(Nellcor Puritan Bennett - 395、NPB - 190、NPB - 290、NPB - 40和Surgi - Vet V3304),传感器置于五个部位。在每只动物的三个血红蛋白饱和度平台(98%、85%和72%)下,各进行十次读数(SpO2)测量。同时采集动脉血样,并用血气分析仪测量血红蛋白饱和度。对于每个测试物种中的每个模型,饱和度测量的准确性以均方根差(RMSD)计算,RMSD是偏差和精密度的综合指标。
准确性差异很大。在狗身上,NPB - 395、NPB - 190、NPB - 290、NPB - 40和V3304的RMSD分别为2.7%、2.2%、2.4%、1.7%和2.7%。NPB - 395、NPB - 190、NPB - 290、NPB - 40和V3304无法读数的比例分别为0、0、0.7%、0和20%。舌头、脚趾、耳朵、嘴唇和包皮或外阴部位的皮尔逊相关系数分别为0.95、0.97、0.69、0.87和0.95。在马身上,NPB - 395、NPB - 190、NPB - 290、NPB - 40和V3304的RMSD分别为3.1%、3.0%、4.7%、3.3%和2.1%,而无法读数的比例分别为10%、21%、0、17%和60%。舌头、鼻孔、耳朵、嘴唇和包皮或外阴部位的皮尔逊相关系数分别为0.98、0.94、0.88、0.93和0.94。在猫身上,NPB - 395、NPB - 190、NPB - 290、NPB - 40和V3304所有数据的RMSD分别为5.9%、5.6%、7.9%、7.9%和10.7%,而失败率分别为0、0.7%、0、20%和32%。舌头、后爪、耳朵、嘴唇和前爪的相关系数分别为0.54、0.79、0.64、0.49和0.57。对于猫身上饱和度高于9%的情况,NPB - 395、NPB - 190、NPB - 290、NPB - 40和V3304的RMSD分别为2.6%、4.4%、4.0%、3.5%和4.8%,而失败率分别为0、1.7%、0、25%和43%。
不同型号之间以及不同物种之间,准确性和失败率(无法读数)差异很大。一般来说,在临床相关范围(90% - 100%)内测试的模型中,RMSD在2% - 5%之间,而V3304的失败率最高。