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在急性受伤且有凝血功能障碍的患者中,使用离心式涡流血泵和肝素结合回路进行严重低温的体外复温。

Use of a centrifugal vortex blood pump and heparin-bonded circuit for extracorporeal rewarming of severe hypothermia in acutely injured and coagulopathic patients.

作者信息

Kirkpatrick Andrew W, Garraway Naisan, Brown David Ross, Nash David, Ng Alexander, Lawless Bernard, Cunningham Johan, Chun Rosaleen, Simons Richard K

机构信息

Department of Critical Care Medicine and Surgery, Foothills Medical Centre, Calgary, Alberta, Canada.

出版信息

J Trauma. 2003 Sep;55(3):407-12. doi: 10.1097/01.TA.0000078693.35083.20.

DOI:10.1097/01.TA.0000078693.35083.20
PMID:14501879
Abstract

BACKGROUND

Standard rewarming methods for posttraumatic hypothermia are ineffective or require systemic heparinization. Centrifugal vortex blood pumps (CVBPs), heparin-bonded circuits, and, potentially, percutaneous access techniques, facilitate the institution of an extracorporeal circulation by noncardiac surgeons.

METHODS

Seven severely hypothermic patients requiring emergent operative intervention were rewarmed intraoperatively using the CVBP with heparin-bonded circuitry.

RESULTS

Patients were critically ill (average Injury Severity Score of 43.5 [SD, 13.6] for the traumatized patients). The mean temperature before rewarming was 31.5 degrees C (SD, 1.6 degrees C). The CVBP outflow site was the common femoral vein in all patients, with the inflow into the superficial femoral artery (n = 2), contralateral common femoral vein (n = 2), and internal jugular vein (n = 3). The mean time to rewarm to 37 degrees C was 73.3 (SD, 30.5) minutes. All patients survived the initial operation, although the ultimate survival was 43%.

CONCLUSION

Noncardiac surgeons can effectively use an extracorporeal rewarming strategy incorporating a heparin-bonded CVBP to rapidly rewarm hypothermic coagulopathic patients undergoing surgery.

摘要

背景

创伤后体温过低的标准复温方法无效或需要全身肝素化。离心式涡流血泵(CVBP)、肝素涂层回路以及经皮穿刺技术可能有助于非心脏外科医生建立体外循环。

方法

7例需要紧急手术干预的严重体温过低患者在术中使用带肝素涂层回路的CVBP进行复温。

结果

患者病情危急(创伤患者的平均损伤严重度评分为43.5 [标准差,13.6])。复温前的平均体温为31.5℃(标准差,1.6℃)。所有患者的CVBP流出部位均为股总静脉,流入部位为股浅动脉(2例)、对侧股总静脉(2例)和颈内静脉(3例)。复温至37℃的平均时间为73.3(标准差,30.5)分钟。所有患者均在初次手术中存活,尽管最终生存率为43%。

结论

非心脏外科医生可以有效地采用一种包含肝素涂层CVBP的体外复温策略,为接受手术的体温过低的凝血病患者快速复温。

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