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上皮样肉瘤的DNA流式细胞术

DNA flow cytometry of epithelioid sarcoma.

作者信息

Pastel-Levy C, Bell D A, Rosenberg A E, Preffer F, Colvin R B, Flotte T J

机构信息

Department of Pathology, Massachusetts General Hospital, Boston 02114.

出版信息

Cancer. 1992 Dec 15;70(12):2823-6. doi: 10.1002/1097-0142(19921215)70:12<2823::aid-cncr2820701216>3.0.co;2-9.

DOI:10.1002/1097-0142(19921215)70:12<2823::aid-cncr2820701216>3.0.co;2-9
PMID:1451061
Abstract

DNA ploidy of paraffin-embedded tissue from 11 patients with epithelioid sarcoma and 20 control specimens (granuloma annulare and sarcoid) was studied. DNA aneuploidy was found in 64% of the epithelioid sarcomas and in none of the control samples. Aneuploidy did not correlate with necrosis, vascular invasion, or mitotic rate. There was also no association of aneuploidy with adverse outcome.

摘要

对11例上皮样肉瘤患者石蜡包埋组织及20个对照标本(环状肉芽肿和结节病)的DNA倍性进行了研究。在64%的上皮样肉瘤中发现了DNA非整倍体,而对照样本中均未发现。非整倍体与坏死、血管侵犯或有丝分裂率无关。非整倍体与不良预后也无关联。

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DNA flow cytometry of epithelioid sarcoma.上皮样肉瘤的DNA流式细胞术
Cancer. 1992 Dec 15;70(12):2823-6. doi: 10.1002/1097-0142(19921215)70:12<2823::aid-cncr2820701216>3.0.co;2-9.
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[Flow cytometric analysis of DNA from 98 cases of soft tissue tumors and its clinical significance].
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