Pastel-Levy C, Bell D A, Rosenberg A E, Preffer F, Colvin R B, Flotte T J
Department of Pathology, Massachusetts General Hospital, Boston 02114.
Cancer. 1992 Dec 15;70(12):2823-6. doi: 10.1002/1097-0142(19921215)70:12<2823::aid-cncr2820701216>3.0.co;2-9.
DNA ploidy of paraffin-embedded tissue from 11 patients with epithelioid sarcoma and 20 control specimens (granuloma annulare and sarcoid) was studied. DNA aneuploidy was found in 64% of the epithelioid sarcomas and in none of the control samples. Aneuploidy did not correlate with necrosis, vascular invasion, or mitotic rate. There was also no association of aneuploidy with adverse outcome.
对11例上皮样肉瘤患者石蜡包埋组织及20个对照标本(环状肉芽肿和结节病)的DNA倍性进行了研究。在64%的上皮样肉瘤中发现了DNA非整倍体,而对照样本中均未发现。非整倍体与坏死、血管侵犯或有丝分裂率无关。非整倍体与不良预后也无关联。