格氏豆酮D，一种从格氏崖豆藤根皮中提取的具有抗炎活性的异黄酮。
Griffonianone D, an isoflavone with anti-inflammatory activity from the root bark of Millettia griffoniana.
作者信息
Yankep Emmanuel, Njamen Dieudonné, Fotsing Maurice Tagatsing, Fomum Zacharias Tanee, Mbanya Jean-Claude, Giner Rosa M, Recio M Carmen, Máñez Salvador, Ríos José Luis
机构信息
Department of Organic Chemistry, Faculty of Science, University of Yaounde 1, P.O. Box 812 Yaounde, Cameroon.
出版信息
J Nat Prod. 2003 Sep;66(9):1288-90. doi: 10.1021/np0205912.
A new isoflavone, griffonianone D (1), and the previously known compounds durmillone and odorantin were isolated from a chloroform extract of the root bark of Millettia griffoniana. The structure of 1 was established as (7E)-(6",7"-dihydroxy-3",7"-dimethyloct-2"-enyl)oxy-4'-methoxyisoflavone on the basis of its spectral data. The chloroform extract of the root bark of M. griffoniana and compound 1 showed anti-inflammatory effects in different experimental models of inflammation.
从格氏崖豆藤根皮的氯仿提取物中分离出一种新的异黄酮——格氏异黄酮D（1），以及先前已知的化合物杜米酮和奥多兰汀。根据其光谱数据，将1的结构确定为（7E）-（6″，7″-二羟基-3″，7″-二甲基辛-2″-烯基）氧基-4'-甲氧基异黄酮。格氏崖豆藤根皮的氯仿提取物和化合物1在不同的炎症实验模型中均显示出抗炎作用。
Zotero 插件