Koike Kenta, Iihara Masatoshi, Kanbe Masako, Omi Yoko, Aiba Motohiko, Obara Takao
Department of Endocrine Surgery, Tokyo Women's Medical University, Tokyo, Japan.
Surg Today. 2003;33(10):785-90. doi: 10.1007/s00595-003-2565-8.
A case of ganglioneuroblastoma in the adrenal gland of a 50-year-old man is reported. The patient was incidentally found to have a nonfunctioning tumor in the right adrenal gland. The tumor, measuring 4.5 cm, was successfully removed using laparoscopy. Histologically, the tumor was diagnosed to be a ganglioneuroblastoma. Immunohistochemically, a few MIB-1-positive cells and no S-100 protein-positive cells were observed. There has been no evidence of recurrence for 2.5 years to date after the operation. Adrenal ganglioneuroblastoma is extremely rare in adults, and only seven such cases have been previously reported in the literature.
报告了一例50岁男性肾上腺神经节神经母细胞瘤病例。该患者偶然发现右肾上腺有一个无功能肿瘤。肿瘤大小为4.5厘米,通过腹腔镜手术成功切除。组织学上,该肿瘤被诊断为神经节神经母细胞瘤。免疫组织化学检查发现少数MIB-1阳性细胞,未观察到S-100蛋白阳性细胞。术后至今2.5年无复发迹象。肾上腺神经节神经母细胞瘤在成人中极为罕见,此前文献中仅报道过7例此类病例。