Bernstein Rachel C, Yalcinkaya Tamer M
West Virginia University School of Medicine, Morgantown, USA.
W V Med J. 2003 May-Jun;99(3):105-7.
To evaluate if Chlamydia trachomatis IgG serology combined with hysterosalpingography can make it easier to detect tuboperitoneal factor infertility, we conducted a chart review of 76 consecutive patients at an infertility practice at West Virginia University from 1999-2001. We checked the charts for results of Chlamydia trachomatis IgG serology, Hysterosalpingography (HSG) and laparoscopy. Results of these tests were reviewed along with age, parity, previous reproductive tract disease surgery and duration of infertility. Complete data was found on 32 of the 76 patients. Chlamydia serology in conjunction with the HSG had a sensitivity of 80% for tuboperitoneal factor (tubal obstruction or pelvic adhesions), and a specificity of 82.3%. The positive predictive value was 80% and the negative predictive value was 82%. Since Chlamdia trachomatis IgG serologic testing is non-invasive and relatively inexpensive, we recommend combining it with hysterosalpingography as an infertility work-up. More invasive testing such as laparoscopy may be postponed or completely eliminated.
为评估沙眼衣原体IgG血清学检查联合子宫输卵管造影术是否能更易于检测出输卵管腹膜因素导致的不孕症，我们对1999年至2001年期间在西弗吉尼亚大学不孕症诊所连续就诊的76例患者的病历进行了回顾。我们查阅了病历中沙眼衣原体IgG血清学检查、子宫输卵管造影术（HSG）和腹腔镜检查的结果。这些检查结果与患者的年龄、产次、既往生殖道疾病手术史及不孕持续时间一同进行了分析。76例患者中有32例具备完整数据。沙眼衣原体血清学检查联合子宫输卵管造影术对输卵管腹膜因素（输卵管阻塞或盆腔粘连）的敏感性为80%，特异性为82.3%。阳性预测值为80%，阴性预测值为82%。鉴于沙眼衣原体IgG血清学检测是非侵入性的且相对廉价，我们建议将其与子宫输卵管造影术联合用于不孕症检查。诸如腹腔镜检查等侵入性更强的检查可能会被推迟或完全取消。
