• 文献检索
  • 文档翻译
  • 深度研究
  • 学术资讯
  • Suppr Zotero 插件Zotero 插件
  • 邀请有礼
  • 套餐&价格
  • 历史记录
应用&插件
Suppr Zotero 插件Zotero 插件浏览器插件Mac 客户端Windows 客户端微信小程序
定价
高级版会员购买积分包购买API积分包
服务
文献检索文档翻译深度研究API 文档MCP 服务
关于我们
关于 Suppr公司介绍联系我们用户协议隐私条款
关注我们

Suppr 超能文献

核心技术专利:CN118964589B侵权必究
粤ICP备2023148730 号-1Suppr @ 2026

文献检索

告别复杂PubMed语法,用中文像聊天一样搜索,搜遍4000万医学文献。AI智能推荐,让科研检索更轻松。

立即免费搜索

文件翻译

保留排版,准确专业,支持PDF/Word/PPT等文件格式,支持 12+语言互译。

免费翻译文档

深度研究

AI帮你快速写综述,25分钟生成高质量综述,智能提取关键信息,辅助科研写作。

立即免费体验

内镜手术在治疗污染和感染性滑膜腔中的应用。

Endoscopic surgery in the treatment of contaminated and infected synovial cavities.

作者信息

Wright I M, Smith M R W, Humphrey D J, Eaton-Evans T C J, Hillyer M H

机构信息

Reynolds House Referrals, Greenwood Ellis & Partners, 166 High Street, Newmarket, Suffolk CB8 9WS, UK.

出版信息

Equine Vet J. 2003 Sep;35(6):613-9. doi: 10.2746/042516403775467225.

DOI:10.2746/042516403775467225
PMID:14515964
Abstract

REASONS FOR PERFORMING STUDY

Contamination and infection of synovial cavities are a common occurrence in clinical practice and, if inadequately treated, may have career or life threatening consequences for affected horses.

HYPOTHESIS

The objectives in treating contamination and infection of joints, tendon sheaths and bursae are most effectively met by endoscopic surgery.

METHODS

Over a 6 year period, cases of synovial contamination and infection admitted to a referral clinic were evaluated and treated endoscopically. The horses received local and systemic antimicrobial drugs with minimal nonsteroidal anti-inflammatory medication but no other medical or surgical treatment. All arthroscope and instrument portals and, whenever possible, all traumatic wounds were closed. Diagnostic information, endoscopic observations and results of treatment were evaluated retrospectively.

RESULTS

A total of 140 affected animals were referred and 121 cases were treated endoscopically. These involved 70 joints, 29 tendon sheaths, 10 bursae and in 12 cases a combination of synovial cavities. The most common aetiologies were open wounds (n = 54) and self-sealing punctures (n = 41). Foreign material was identified endoscopically in 41 but predicted prior to surgery in only 6 cases. Osteochondral lesions were evident at surgery in 51 and recognised before surgery in 25 cases; 32 horses had intrathecal tendon or ligament defects. Follow-up information was obtained for 118 animals; 106 (90%) survived and 96 (81%) returned to their preoperative level of performance. The presence of osteitis/osteomyelitis, other osteochondral lesions and marked deposits of pannus were associated with nonsurvival. For those animals which survived, non-Thoroughbred horses, a combination of synovial structure involvement and regional i.v. antimicrobial administration were associated with reduced post operative performance. Marked pannus, regional i.v. antimicrobial administration and duration of systemic antimicrobial administration were associated with a group combining nonsurviving animals and those with reduced post operative performance.

CONCLUSIONS

Endoscopic surgery makes a valuable contribution to the management of synovial contamination and infection.

POTENTIAL RELEVANCE

The information obtained from and therapeutic options offered by endoscopy justify its early use in cases of synovial contamination and infection.

摘要

开展本研究的原因

滑膜腔的污染和感染在临床实践中很常见,若治疗不当,可能会对患病马匹造成危及职业生涯或生命的后果。

假设

通过内镜手术能最有效地实现治疗关节、腱鞘和滑囊污染及感染的目标。

方法

在6年期间,对转诊至一家专科诊所的滑膜污染和感染病例进行评估并实施内镜治疗。马匹接受局部和全身抗菌药物治疗,同时尽量减少非甾体抗炎药的使用,未接受其他药物或手术治疗。所有关节镜和器械入口以及所有创伤性伤口尽可能进行缝合。对诊断信息、内镜观察结果和治疗效果进行回顾性评估。

结果

共转诊140只患病动物,其中121例接受了内镜治疗。这些病例涉及70个关节、29个腱鞘、10个滑囊,12例为多个滑膜腔合并感染。最常见的病因是开放性伤口(n = 54)和自封性穿刺伤(n = 41)。内镜检查发现41例存在异物,但术前仅预测到6例。手术中发现51例存在骨软骨损伤,术前诊断出25例;32匹马存在鞘内肌腱或韧带缺损。获得了118只动物的随访信息;106只(90%)存活,96只(81%)恢复到术前的运动水平。存在骨炎/骨髓炎、其他骨软骨损伤和明显的血管翳沉积与死亡相关。对于存活的动物,非纯种马、滑膜结构受累和局部静脉注射抗菌药物与术后运动水平下降有关。明显的血管翳、局部静脉注射抗菌药物和全身抗菌药物使用时间与死亡动物及术后运动水平下降的动物组合有关。

结论

内镜手术对滑膜污染和感染的治疗有重要贡献。

潜在意义

内镜检查所获得的信息及提供的治疗选择证明其在滑膜污染和感染病例中应尽早使用。

相似文献

1
Endoscopic surgery in the treatment of contaminated and infected synovial cavities.内镜手术在治疗污染和感染性滑膜腔中的应用。
Equine Vet J. 2003 Sep;35(6):613-9. doi: 10.2746/042516403775467225.
2
Synovial sepsis of unknown origin in the adult Thoroughbred racehorse.成年纯血赛马不明原因的滑膜脓毒症。
Equine Vet J. 2020 Jan;52(1):91-97. doi: 10.1111/evj.13127. Epub 2019 May 20.
3
Post operative synovial sepsis following endoscopic surgery: Increased risk associated with the carpal sheath.内镜手术后的滑膜败血症:与腕管腱鞘相关的风险增加
Equine Vet J. 2016 Jul;48(4):430-3. doi: 10.1111/evj.12472. Epub 2015 Aug 14.
4
[Direct endoscopic approach improves prognosis of septic-synovitis in the horse].[直接内镜手术改善马的化脓性滑膜炎预后]
Tijdschr Diergeneeskd. 2002;127(14-15):444-9.
5
Arthroscopic laser extirpation of metacarpophalangeal synovial pad proliferation in eleven horses.
Equine Vet J. 2001 May;33(3):296-301. doi: 10.2746/042516401776249679.
6
Metacarpophalangeal joint synovial pad fibrotic proliferation in 63 horses.63匹马的掌指关节滑膜垫纤维化增生
Vet Surg. 1996 May-Jun;25(3):199-206. doi: 10.1111/j.1532-950x.1996.tb01399.x.
7
Endoscopy of the navicular bursa: a new technique for the treatment of contaminated and septic bursae.舟状滑囊内镜检查:一种治疗污染性和感染性滑囊的新技术。
Equine Vet J. 1999 Jan;31(1):5-11. doi: 10.1111/j.2042-3306.1999.tb03784.x.
8
A multi-centre cohort study investigating the outcome of synovial contamination or sepsis of the calcaneal bursae in horses treated by endoscopic lavage and debridement.一项多中心队列研究调查了通过内镜灌洗和清创术治疗的马的跟腱滑液囊滑膜污染或脓毒症的结局。
Equine Vet J. 2020 May;52(3):404-410. doi: 10.1111/evj.13180. Epub 2019 Oct 16.
9
Factors associated with survival to hospital discharge following endoscopic treatment for synovial sepsis in 214 horses.214匹马滑膜脓毒症内镜治疗后出院存活相关因素。
Equine Vet J. 2014 Nov;46(6):701-5. doi: 10.1111/evj.12212. Epub 2014 Jan 12.
10
Treatment with continuous intrasynovial antimicrobial infusion for septic synovitis in horses: 31 cases (2000-2003).连续滑膜内抗菌药物输注治疗马的化脓性滑膜炎:31例(2000 - 2003年)
J Am Vet Med Assoc. 2006 Jun 15;228(12):1922-9. doi: 10.2460/javma.228.12.1922.

引用本文的文献

1
Efficacy of needle and endoscopic lavage on the recuperation of microspheres from the adult equine metacarpo-/metatarsophalangeal joint and digital flexor tendon sheath.针灌洗和内镜灌洗对成年马掌指/跖趾关节及指屈肌腱鞘内微球回收的效果
Vet Surg. 2025 Aug;54(6):1157-1166. doi: 10.1111/vsu.14298. Epub 2025 Jun 25.
2
Equine Distal Limb Wounds: Economic Impact and Short-Term Prognosis of Non-Synovial Versus Synovial Lesions in Southern Germany.马的远端肢体伤口:德国南部非滑膜性与滑膜性损伤的经济影响及短期预后
Vet Sci. 2025 Mar 1;12(3):205. doi: 10.3390/vetsci12030205.
3
Clinical use of antimicrobial regional limb perfusion in adult horses diagnosed with synovial sepsis or penetrating synovial wounds at a single equine referral hospital in the Midwest United States-163 cases (2010-2020).
在美国中西部一家大型动物转诊医院,对163例(2010 - 2020年)被诊断为滑膜败血症或穿透性滑膜伤口的成年马进行抗菌区域肢体灌注的临床应用。
Front Vet Sci. 2025 Mar 26;12:1504486. doi: 10.3389/fvets.2025.1504486. eCollection 2025.
4
TLR-activated mesenchymal stromal cell therapy and antibiotics to treat multi-drug resistant septic arthritis in an equine model.在马模型中,采用Toll样受体激活的间充质基质细胞疗法和抗生素治疗多重耐药性化脓性关节炎。
Ann Transl Med. 2022 Nov;10(21):1157. doi: 10.21037/atm-22-1746.
5
Case report: Primary chronic calcaneal bursitis treated with subtotal bursectomy in a cat.病例报告:猫原发性慢性跟腱囊炎行跟腱囊次全切除术治疗
Front Vet Sci. 2022 Sep 12;9:915741. doi: 10.3389/fvets.2022.915741. eCollection 2022.
6
A Descriptive Study of the Clinical Presentation, Management, and Outcome of Horses with Acute Soft Tissue Trauma of the Tarsus and the Association with Synovial Involvement.跗关节急性软组织创伤马匹的临床表现、治疗及预后的描述性研究及其与滑膜受累的关系
Animals (Basel). 2022 Feb 21;12(4):524. doi: 10.3390/ani12040524.
7
Comparison of equine synovial sepsis rate following intrasynovial injection in ambulatory versus hospital settings.门诊与住院环境下关节内注射后马属动物滑膜炎发生率的比较。
Equine Vet J. 2022 May;54(3):523-530. doi: 10.1111/evj.13485. Epub 2021 Jul 8.
8
Evaluation of Intra-Articular Amikacin Administration in an Equine Non-inflammatory Joint Model to Identify Effective Bactericidal Concentrations While Minimizing Cytotoxicity.在马非炎性关节模型中评估关节腔内注射阿米卡星,以确定有效的杀菌浓度,同时将细胞毒性降至最低。
Front Vet Sci. 2021 May 21;8:676774. doi: 10.3389/fvets.2021.676774. eCollection 2021.
9
Detection of synovial sepsis in horses using enzymes as biomarkers.利用酶作为生物标志物检测马的滑膜脓毒症。
Equine Vet J. 2022 May;54(3):513-522. doi: 10.1111/evj.13459. Epub 2021 Jun 15.
10
Use of serum amyloid A in serum and synovial fluid to detect eradication of infection in experimental septic arthritis in horses.利用血清淀粉样蛋白 A 在血清和滑液中检测马实验性脓毒性关节炎感染的清除。
Can J Vet Res. 2020 Jul;84(3):198-204.