Hokama Akira, Kinjo Fukunori, Arakaki Tamiki, Matayoshi Ryoji, Yonamine Yoshimasa, Tomiyama Ryosaku, Sunagawa Takashi, Makishi Tomoko, Kawane Mariko, Koja Kageharu, Saito Atsushi
First Department of Internal Medicine, University of the Ryukyus, Uehara, Nishihara, Okinawa.
Intern Med. 2003 Sep;42(9):897-8. doi: 10.2169/internalmedicine.42.897.
A 36-year-old woman with ulcerative colitis presented with fever, chest and back pain, and fatigue sensation of the arm. Her upper limb pulses were absent. Angiography showed multiple aneurysms of the aorta and its branches, consistent with Takayasu's arteritis. She showed HLA-B35 but no B52, which is the typical haplotype among the coexistence cases of both diseases. Prednisolone was effective. The possible pathogenic association of the disorders is discussed.
一名36岁的溃疡性结肠炎女性患者出现发热、胸痛、背痛以及手臂乏力感。她的上肢脉搏消失。血管造影显示主动脉及其分支存在多个动脉瘤,符合高安动脉炎。她显示有HLA - B35,但没有B52,而B52是这两种疾病共存病例中的典型单倍型。泼尼松龙治疗有效。文中讨论了这两种疾病可能的致病关联。