Chapman R F, Bernays E A, Singer M S, Hartmann T
Division of Neurobiology, University of Arizona, PO Box 210077, Tucson, AZ 85721-0077, USA.
J Comp Physiol A Neuroethol Sens Neural Behav Physiol. 2003 Nov;189(11):833-41. doi: 10.1007/s00359-003-0461-8. Epub 2003 Sep 30.
Electrophysiological recordings from taste sensilla of the caterpillar Estigmene acrea with the pyrrolizidine alkaloid, seneciphylline N-oxide, demonstrated that prior feeding on plants with pyrrolizidine alkaloids caused an increase in responsiveness of the PA-sensitive cells in two sensilla, relative to feeding on plants without such chemicals. Rearing on synthetic diet without pyrrolizidine alkaloids for up to seven generations caused a continuous decline in responsiveness, that could be reversed by experience with powdered Crotalaria pumila in the diet or by pure pyrrolizidine alkaloid, monocrotaline, in the diet. Response to the cardiac glycoside, ouabain, that stimulates one of the two pyrrolizidine alkaloid-sensitive cells, showed a similar decline. Pyrrolizidine alkaloids had no measurable effect on growth and development. Responses in all other taste cells were unaffected. The data are discussed in relation to the possible adaptive significance and the possible mechanisms involved.
对取食含有吡咯里西啶生物碱氧化千里光碱的美国白蛾幼虫味觉感受器进行的电生理记录表明，与取食不含此类化学物质的植物相比，此前取食含吡咯里西啶生物碱的植物会使两个感受器中对PA敏感的细胞的反应性增强。在不含吡咯里西啶生物碱的合成饲料中饲养多达七代，会导致反应性持续下降，而通过在饲料中添加粉状猪屎豆或纯吡咯里西啶生物碱野百合碱的经历可以使其逆转。对刺激两个对吡咯里西啶生物碱敏感的细胞之一的强心苷哇巴因的反应也呈现出类似的下降。吡咯里西啶生物碱对生长发育没有可测量的影响。所有其他味觉细胞的反应不受影响。文中讨论了这些数据的可能适应性意义和涉及的可能机制。
