突尼斯南部白癜风概况
Profile of vitiligo in the south of Tunisia.
作者信息
Akrem Jalel, Baroudi Aicha, Aichi Taher, Houch Fethi, Hamdaoui Mohamed Hédi
机构信息
Unité de Recherche sur les Composés Antioxydants, Stress Oxydant, Eléments Traces et Maladies Métaboliques, Ecole Supérieure des Sciences et Techniques de la Santé de Tunis, Tunis, Tunisia.
出版信息
Int J Dermatol. 2008 Jul;47(7):670-4. doi: 10.1111/j.1365-4632.2008.03695.x.
BACKGROUND
Vitiligo is a depigmentation disorder characterized by the loss of melanocytes from cutaneous cells. Its pathogenesis has not yet been clarified.
OBJECTIVE
To study the epidemiologic profile of vitiligo in Tunisia and analyze its characteristics.
METHODS
The clinical presentation of vitiligo was examined in 60 patients [27 males (45%) and 33 females (55%)] attending the Médenine Hospital Center, a large hospital in the south of Tunisia.
RESULTS
The lower limbs were the initial site of onset of vitiligo in the majority of patients (29.8%), followed by the upper limbs, head and neck, trunk, and mucosae. The most common clinical pattern observed was vitiligo vulgaris, followed by focal, acrofacial, mucosal, segmental, and universal types. Leukotrichia was observed in 23%, koebnerization in 18.5%, and a positive family history in 18%.
CONCLUSION
This study indicates that vitiligo vulgaris is the most common clinical type observed in the south of Tunisia. There were associated endocrine disorders in some patients, including diabetes, hypothyroidism, and alopecia.
背景
白癜风是一种色素脱失性疾病，其特征是皮肤细胞中的黑素细胞丧失。其发病机制尚未阐明。
目的
研究突尼斯白癜风的流行病学概况并分析其特征。
方法
对就诊于突尼斯南部一家大型医院——梅德宁医院中心的60例患者[27例男性（45%）和33例女性（55%）]的白癜风临床表现进行了检查。
结果
大多数患者（29.8%）白癜风的首发部位是下肢，其次是上肢、头颈部、躯干和黏膜。观察到的最常见临床类型为寻常型白癜风，其次是局限型、肢端颜面型、黏膜型、节段型和泛发型。23%的患者出现白发，18.5%的患者有同形反应，18%的患者有阳性家族史。
结论
本研究表明，寻常型白癜风是突尼斯南部观察到的最常见临床类型。一些患者存在相关的内分泌紊乱，包括糖尿病、甲状腺功能减退和脱发。
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