Navder K P, Fryer E B, Fryer H C
Kansas Agricultural Experiment Station, Kansas State University, Manhattan 66506.
Indian J Med Sci. 1992 Sep;46(9):275-80.
Acceleration of cholesterol catabolism (through feces) has been proposed as one of the mechanisms for the hypocholesterolemic effect of dairy products. This study examined the effects of feeding two milk products (skim milk and skim milk yogurt) on fecal neutral sterol excretions in rats. Six groups of nine rats each were fed iso-caloric Chow-based diets containing water, 45% skim milk (SM), or 45% skim milk yogurt (SMY), without or with cholesterol. The results indicate that both SM and SMY increased the excretion of total neutral sterols under hyperlipemic conditions. The SMY diet (with cholesterol) also increased the excretion of coprostanol, a bacterial metabolite.
胆固醇分解代谢加速（通过粪便排出）被认为是乳制品降胆固醇作用的机制之一。本研究检测了喂食两种奶制品（脱脂牛奶和脱脂酸奶）对大鼠粪便中性固醇排泄的影响。将六组大鼠，每组九只，分别喂食以高热量食物为基础的饮食，这些饮食含有水、45%的脱脂牛奶（SM）或45%的脱脂酸奶（SMY），分别添加或不添加胆固醇。结果表明，在高脂血症条件下，SM和SMY均增加了总中性固醇的排泄。含胆固醇的SMY饮食还增加了细菌代谢产物粪甾烷醇的排泄。
