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二倍体可交换种群模型中的溯祖模式

Coalescent patterns in diploid exchangeable population models.

作者信息

Möhle Martin, Sagitov Serik

机构信息

Eberhard Karls University of Tübingen, Mathematics Institute, 72076 Tübingen, Germany.

出版信息

J Math Biol. 2003 Oct;47(4):337-52. doi: 10.1007/s00285-003-0218-6. Epub 2003 May 15.

DOI:10.1007/s00285-003-0218-6
PMID:14523577
Abstract

A class of two-sex population models is considered with N females and equal number N of males constituting each generation. Reproduction is assumed to undergo three stages: 1) random mating, 2) exchangeable reproduction, 3) random sex assignment. Treating individuals as pairs of genes at a certain locus we introduce the diploid ancestral process (the past genealogical tree) for n such genes sampled in the current generation. Neither mutation nor selection are assumed. A convergence criterium for the diploid ancestral process is proved as N goes to infinity while n remains unchanged. Conditions are specified when the limiting process (coalescent) is the Kingman coalescent and situations are discussed when the coalescent allows for multiple mergers of ancestral lines.

摘要

考虑一类两性种群模型,其中每一代由(N)名雌性和数量相等的(N)名雄性组成。假设繁殖经历三个阶段:1)随机交配,2)可交换繁殖,3)随机性别分配。将个体视为某一位点上的基因对,我们引入了当前一代中抽取的(n)个此类基因的二倍体祖先过程(过去的系谱树)。假设既没有突变也没有选择。证明了随着(N)趋于无穷而(n)保持不变时二倍体祖先过程的收敛准则。指定了极限过程(合并过程)为金曼合并过程的条件,并讨论了合并过程允许祖先线多重合并的情况。

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