Ogino H, Watanabe E, Watanabe S, Agawa H, Narita M, Haritani M, Kawashima K
Chuo Livestock Hygiene Service Center, Niigata, Japan.
J Comp Pathol. 1992 Aug;107(2):231-7. doi: 10.1016/0021-9975(92)90039-w.
Protozoal encephalitic lesions were found in four aborted fetuses and one dead newborn calf. The organism was identified as Neospora caninum by immunoperoxidase. The brain lesions were of two forms. One was observed in three fetuses of 5 months gestation and was characterized by multifocal necrosis. The other was found in a 7-month fetus and in a newborn calf, and showed severe infiltration with macrophages and plasma cells containing IgG. This association, between the age of fetus and inflammation, may reflect development of the immune system in bovine fetuses.
在四头流产胎儿和一头新生死亡小牛中发现了原生动物脑炎性病变。通过免疫过氧化物酶法将该生物体鉴定为犬新孢子虫。脑病变有两种形式。一种在3头妊娠5个月的胎儿中观察到，其特征为多灶性坏死。另一种在一头7个月大的胎儿和一头新生小牛中发现，表现为含有IgG的巨噬细胞和浆细胞的严重浸润。胎儿年龄与炎症之间的这种关联可能反映了牛胎儿免疫系统的发育情况。
