Cheng Haiying, Luo Qingming, Wang Zheng, Gong Hui, Chen Shangbin, Liang Wenxi, Zeng Shaoqun
The Key Laboratory of Biomedical Photonics of the Ministry of Education, Huazhong University of Science and Technology, Wuhan, Hubei 430074, China.
Appl Opt. 2003 Oct 1;42(28):5759-64. doi: 10.1364/ao.42.005759.
We present a noninvasive full-field method--laser speckle imaging (LSI)--for measuring the regional mesenteric blood flow without scanning. A system of LSI was designed and validated in a model experiment. Dynamics of regional blood flow in the rat mesentery under the influence of noradrenaline were monitored by this method. Spatial and temporal characteristics of the mesenteric blood-flow response were achieved with high resolution. These suggested that LSI might provide a new approach to microcirculation studies.
