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连续粒细胞输注治疗中性粒细胞减少患者因多重耐药铜绿假单胞菌引起的败血症。

Serial granulocyte transfusions as a treatment for sepsis due to multidrug-resistant Pseudomonas aeruginosa in a neutropenic patient.

作者信息

Lin Ying-Wei, Adachi Souichi, Watanabe Ken-Ichiro, Umeda Katsutsugu, Nakahata Tatsutoshi

机构信息

Department of Pediatrics, Graduate School of Medicine, Kyoto University, Shogoin, Sakyo-ku, Kyoto 606-8507, Japan.

出版信息

J Clin Microbiol. 2003 Oct;41(10):4892-3. doi: 10.1128/JCM.41.10.4892-4893.2003.

Abstract

The emergence of multidrug-resistant Pseudomonas aeruginosa (MRPA) has become a major clinical problem. We successfully treated MRPA sepsis in a neutropenic patient undergoing peripheral blood stem cell transplantation with serial granulocyte transfusions. Granulocyte transfusion should be considered as a treatment for severe infection in patients with neutropenia.

摘要

多重耐药铜绿假单胞菌(MRPA)的出现已成为一个主要的临床问题。我们通过连续输注粒细胞成功治疗了一名接受外周血干细胞移植的中性粒细胞减少患者的MRPA败血症。粒细胞输注应被视为中性粒细胞减少患者严重感染的一种治疗方法。

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Is it time for a new look at granulocyte transfusions?是时候重新审视粒细胞输注了吗?
Transfusion. 2002 Nov;42(11):1393-5. doi: 10.1046/j.1537-2995.2002.00296.x.
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Effects of storage of granulocytes on their fate in vivo.粒细胞储存对其体内命运的影响。
Transfusion. 1983 Jan-Feb;23(1):20-4. doi: 10.1046/j.1537-2995.1983.23183147298.x.

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